Effectiveness and safety of lubiprostone after switching from stimulant laxatives in elderly patients with chronic constipation

Effectiveness and safety of lubiprostone after switching from stimulant laxatives in elderly patients with chronic constipation

Abstract Background and Aim Stimulant laxatives may cause electrolyte abnormalities, dehydration, and abdominal pain; their long‐term use can lead to tolerance and subsequent refractory constipation. We investigated the effectiveness, safety, and quality of life after switching from stimulant laxati...

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Main Authors: Masaki Maruyama, Suguru Miida, Toshihiro Sato, Takazumi Kimura, Azuma Watanabe, Hideo Watanabe, Masafumi Nishizawa, Kyohei Horikawa, Takahiro Kajiwara, Yusuke Karasawa, Yuko Hasebe, Kazutaka Nozawa, Shuji Terai
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:JGH Open
Subjects:
constipation
drug therapy
elderly
laxatives
lubiprostone
Online Access:https://doi.org/10.1002/jgh3.12956

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