Seroprevalence of severe acute respiratory syndrome coronavirus 2 immunoglobulin G antibodies among health-care workers prior and after 4–6 weeks of coronavirus disease vaccine administration at tertiary care center of southwest Bihar, India
AIM: Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an ongoing global health emergency. To control the spread, a mass vaccination program is initiated. Antibody titer after vaccination can be a better marker to monitor immunological resp...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Indian Journal of Health Sciences and Biomedical Research KLEU |
| Subjects: | |
| Online Access: | http://www.ijournalhs.org/article.asp?issn=2542-6214;year=2022;volume=15;issue=3;spage=256;epage=260;aulast=Kumar |
| _version_ | 1798021919708020736 |
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| author | Mukesh Kumar Richa Singh Abhishek Kamendu Amit Kumar Singh Jyoti Sangwan |
| author_facet | Mukesh Kumar Richa Singh Abhishek Kamendu Amit Kumar Singh Jyoti Sangwan |
| author_sort | Mukesh Kumar |
| collection | DOAJ |
| description | AIM: Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an ongoing global health emergency. To control the spread, a mass vaccination program is initiated. Antibody titer after vaccination can be a better marker to monitor immunological response.
MATERIALS AND METHODS: The study was carried out at the Department of Microbiology, Narayan Medical College and Hospital, Jamuhar Sasaram, southwest Bihar, considering the sample size, type, and collection. First, antibody was tested before vaccination and second antibody value after 28 days of the first dose of COVID vaccine among the health-care workers and housekeeping staff.
RESULTS: A total of 251 subjects were administered with vaccination (Covishield) to check the immunoglobulin g (IgG) responses. The concentration of the SARS-CoV-2 IgG antibody in female patients tended to be higher than in male patients.
CONCLUSION: There is a difference in antibody positivity among males and females. Most of the participants had IgG positivity, because of their profession, vaccination boosted percentage positivity in both males and females. Females have more IgG levels compared to males. Hence, recommend that separate guidelines can be made between males and females for vaccination dosages. |
| first_indexed | 2024-04-11T17:21:23Z |
| format | Article |
| id | doaj.art-a85ae533a8ae41af915afeb684e003ea |
| institution | Directory Open Access Journal |
| issn | 2542-6214 2542-6222 |
| language | English |
| last_indexed | 2024-04-11T17:21:23Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Health Sciences and Biomedical Research KLEU |
| spelling | doaj.art-a85ae533a8ae41af915afeb684e003ea2022-12-22T04:12:29ZengWolters Kluwer Medknow PublicationsIndian Journal of Health Sciences and Biomedical Research KLEU2542-62142542-62222022-01-0115325626010.4103/kleuhsj.kleuhsj_179_21Seroprevalence of severe acute respiratory syndrome coronavirus 2 immunoglobulin G antibodies among health-care workers prior and after 4–6 weeks of coronavirus disease vaccine administration at tertiary care center of southwest Bihar, IndiaMukesh KumarRicha SinghAbhishek KamenduAmit Kumar SinghJyoti SangwanAIM: Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an ongoing global health emergency. To control the spread, a mass vaccination program is initiated. Antibody titer after vaccination can be a better marker to monitor immunological response. MATERIALS AND METHODS: The study was carried out at the Department of Microbiology, Narayan Medical College and Hospital, Jamuhar Sasaram, southwest Bihar, considering the sample size, type, and collection. First, antibody was tested before vaccination and second antibody value after 28 days of the first dose of COVID vaccine among the health-care workers and housekeeping staff. RESULTS: A total of 251 subjects were administered with vaccination (Covishield) to check the immunoglobulin g (IgG) responses. The concentration of the SARS-CoV-2 IgG antibody in female patients tended to be higher than in male patients. CONCLUSION: There is a difference in antibody positivity among males and females. Most of the participants had IgG positivity, because of their profession, vaccination boosted percentage positivity in both males and females. Females have more IgG levels compared to males. Hence, recommend that separate guidelines can be made between males and females for vaccination dosages.http://www.ijournalhs.org/article.asp?issn=2542-6214;year=2022;volume=15;issue=3;spage=256;epage=260;aulast=Kumar2019 novel coronaviruscoronavirus disease 2019novel coronavirus pneumoniasevere acute respiratory syndrome coronavirus 2 |
| spellingShingle | Mukesh Kumar Richa Singh Abhishek Kamendu Amit Kumar Singh Jyoti Sangwan Seroprevalence of severe acute respiratory syndrome coronavirus 2 immunoglobulin G antibodies among health-care workers prior and after 4–6 weeks of coronavirus disease vaccine administration at tertiary care center of southwest Bihar, India Indian Journal of Health Sciences and Biomedical Research KLEU 2019 novel coronavirus coronavirus disease 2019 novel coronavirus pneumonia severe acute respiratory syndrome coronavirus 2 |
| title | Seroprevalence of severe acute respiratory syndrome coronavirus 2 immunoglobulin G antibodies among health-care workers prior and after 4–6 weeks of coronavirus disease vaccine administration at tertiary care center of southwest Bihar, India |
| title_full | Seroprevalence of severe acute respiratory syndrome coronavirus 2 immunoglobulin G antibodies among health-care workers prior and after 4–6 weeks of coronavirus disease vaccine administration at tertiary care center of southwest Bihar, India |
| title_fullStr | Seroprevalence of severe acute respiratory syndrome coronavirus 2 immunoglobulin G antibodies among health-care workers prior and after 4–6 weeks of coronavirus disease vaccine administration at tertiary care center of southwest Bihar, India |
| title_full_unstemmed | Seroprevalence of severe acute respiratory syndrome coronavirus 2 immunoglobulin G antibodies among health-care workers prior and after 4–6 weeks of coronavirus disease vaccine administration at tertiary care center of southwest Bihar, India |
| title_short | Seroprevalence of severe acute respiratory syndrome coronavirus 2 immunoglobulin G antibodies among health-care workers prior and after 4–6 weeks of coronavirus disease vaccine administration at tertiary care center of southwest Bihar, India |
| title_sort | seroprevalence of severe acute respiratory syndrome coronavirus 2 immunoglobulin g antibodies among health care workers prior and after 4 6 weeks of coronavirus disease vaccine administration at tertiary care center of southwest bihar india |
| topic | 2019 novel coronavirus coronavirus disease 2019 novel coronavirus pneumonia severe acute respiratory syndrome coronavirus 2 |
| url | http://www.ijournalhs.org/article.asp?issn=2542-6214;year=2022;volume=15;issue=3;spage=256;epage=260;aulast=Kumar |
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