Molecular genetic study in a cohort of Iranian families suspected to maturity-onset diabetes of the young, reveals a recurrent mutation and a high-risk variant in the CEL gene

Molecular genetic study in a cohort of Iranian families suspected to maturity-onset diabetes of the young, reveals a recurrent mutation and a high-risk variant in the CEL gene

Background: Diabetes mellitus (DM) is a group of metabolic disorders in the body, accompanied with increasing blood sugar levels. Diabetes is classified into three groups: Type 1 DM (T1DM), Type 2 DM (T2DM), and monogenic diabetes. Maturity-onset diabetes of the young (MODY) is a monogenic diabetes...

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Bibliographic Details
Main Authors: Akram Sarmadi, Aliasgar Mohammadi, Fatemeh Tabatabaei, Zahra Nouri, Morteza Hashemzadeh Chaleshtori, Mohammad Amin Tabatabaiefar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Advanced Biomedical Research
Subjects:
carboxyl ester lipase
maturity-onset diabetes of the young
pathogenic variant
whole-exome sequencing
Online Access:http://www.advbiores.net/article.asp?issn=2277-9175;year=2020;volume=9;issue=1;spage=25;epage=25;aulast=Sarmadi

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