Mucin 1 aggravates synovitis and joint damage of rheumatoid arthritis by regulating inflammation and aggression of fibroblast-like synoviocytes

Mucin 1 aggravates synovitis and joint damage of rheumatoid arthritis by regulating inflammation and aggression of fibroblast-like synoviocytes

AimsTo explore the synovial expression of mucin 1 (MUC1) and its role in rheumatoid arthritis (RA), as well as the possible downstream mechanisms.MethodsPatients with qualified synovium samples were recruited from a RA cohort. Synovium from patients diagnosed as non-inflammatory orthopaedic arthropa...

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Bibliographic Details
Main Authors: Yaoyao Zou, Xuepei Zhang, Jinjian Liang, Liqin Peng, Jiale Qin, Feng Zhou, Ting Liu, Lie Dai
Format: Article
Language:English
Published: The British Editorial Society of Bone & Joint Surgery 2022-09-01
Series:Bone & Joint Research
Subjects:
Rheumatoid arthritis
Fibroblast-like synoviocytes
Mucin 1
Joint destruction
Inflammation
inflammation
Online Access:https://online.boneandjoint.org.uk/doi/10.1302/2046-3758.119.BJR-2021-0398.R2

Internet

https://online.boneandjoint.org.uk/doi/10.1302/2046-3758.119.BJR-2021-0398.R2

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