A reporter cell line for the automated quantification of SARS-CoV-2 infection in living cells

A reporter cell line for the automated quantification of SARS-CoV-2 infection in living cells

The SARS-CoV-2 pandemic and the urgent need for massive antiviral testing highlighted the lack of a good cell-based assay that allowed for a fast, automated screening of antivirals in high-throughput content with minimal handling requirements in a BSL-3 environment. The present paper describes the c...

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Bibliographic Details
Main Authors: Lowiese Desmarets, Nathalie Callens, Eik Hoffmann, Adeline Danneels, Muriel Lavie, Cyril Couturier, Jean Dubuisson, Sandrine Belouzard, Yves Rouillé
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Microbiology
Subjects:
coronavirus
SARS-CoV-2
antivirals
high content imaging
screening
3CLpro
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1031204/full

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