Malignant Transformation of Oral Lichen Planus: A Peril of COVID-19 Pandemic
Oral Lichen Planus (OLP) is a chronic autoimmune inflammatory disease of the oral mucosa. The erosive variety of OLP is multifocal, ulcerative, and painful in nature. Patients with OLP have a higher risk of developing Oral Squamous Cell Carcinomas (OSCCs). Here, authors presents a case of 49-year-...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2021-10-01
|
| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/15502/51282_CE[Ra1]_F[SH]_PF1(SC_SS)_PFA_NC_PN(KM).pdf |
| Summary: | Oral Lichen Planus (OLP) is a chronic autoimmune inflammatory disease of the oral mucosa. The erosive variety of OLP is multifocal,
ulcerative, and painful in nature. Patients with OLP have a higher risk of developing Oral Squamous Cell Carcinomas (OSCCs).
Here, authors presents a case of 49-year-old female patient presented to the Department of Oral Medicine and Radiology with
the chief complaint of burning sensation in the inner aspect of right cheek, since one year. A diffuse whitish area surrounded by
erythematous area was present in the right buccal mucosa. Lesion was diagnosed primarily as erosive Lichen Planus (LP). She
discontinued the medication and did not come for follow-up visits because of the Coronavirus Disease-2019 (COVID-19) pandemic.
After 10 months, she came back with pain and a diffuse swelling with indurated margin in the same region involving right buccal
vestibule and retromolar area. After incisional biopsy it was found that the lesion has progressed to squamous cell carcinoma, and
the patient was referred to the Department of Oral Surgery where segmental mandibulectomy was done with placement of free
fibula graft. The OLP is considered as a potentially malignant disorder and patient should be advised to avoid additional risk factors
such as tobacco and alcohol and should be followed at minimum one year interval as prognosis and patient survival is directly
related to stage and grade of cancer at its initial diagnosis. |
|---|---|
| ISSN: | 2249-782X 0973-709X |