Malignant Transformation of Oral Lichen Planus: A Peril of COVID-19 Pandemic
Oral Lichen Planus (OLP) is a chronic autoimmune inflammatory disease of the oral mucosa. The erosive variety of OLP is multifocal, ulcerative, and painful in nature. Patients with OLP have a higher risk of developing Oral Squamous Cell Carcinomas (OSCCs). Here, authors presents a case of 49-year-...
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JCDR Research and Publications Private Limited
2021-10-01
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| Online Access: | https://jcdr.net/articles/PDF/15502/51282_CE[Ra1]_F[SH]_PF1(SC_SS)_PFA_NC_PN(KM).pdf |
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| author | DEBARATI DEB RUPAM SINHA SUBHADEEP MAITY HARSH VARDHAN JHA Mainak Datta |
| author_facet | DEBARATI DEB RUPAM SINHA SUBHADEEP MAITY HARSH VARDHAN JHA Mainak Datta |
| author_sort | DEBARATI DEB |
| collection | DOAJ |
| description | Oral Lichen Planus (OLP) is a chronic autoimmune inflammatory disease of the oral mucosa. The erosive variety of OLP is multifocal,
ulcerative, and painful in nature. Patients with OLP have a higher risk of developing Oral Squamous Cell Carcinomas (OSCCs).
Here, authors presents a case of 49-year-old female patient presented to the Department of Oral Medicine and Radiology with
the chief complaint of burning sensation in the inner aspect of right cheek, since one year. A diffuse whitish area surrounded by
erythematous area was present in the right buccal mucosa. Lesion was diagnosed primarily as erosive Lichen Planus (LP). She
discontinued the medication and did not come for follow-up visits because of the Coronavirus Disease-2019 (COVID-19) pandemic.
After 10 months, she came back with pain and a diffuse swelling with indurated margin in the same region involving right buccal
vestibule and retromolar area. After incisional biopsy it was found that the lesion has progressed to squamous cell carcinoma, and
the patient was referred to the Department of Oral Surgery where segmental mandibulectomy was done with placement of free
fibula graft. The OLP is considered as a potentially malignant disorder and patient should be advised to avoid additional risk factors
such as tobacco and alcohol and should be followed at minimum one year interval as prognosis and patient survival is directly
related to stage and grade of cancer at its initial diagnosis. |
| first_indexed | 2024-12-20T23:43:16Z |
| format | Article |
| id | doaj.art-a872673bbdb74bd59d192001860c7b22 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-20T23:43:16Z |
| publishDate | 2021-10-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-a872673bbdb74bd59d192001860c7b222022-12-21T19:23:01ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2021-10-011510ZD15ZD1710.7860/JCDR/2021/51282.15502Malignant Transformation of Oral Lichen Planus: A Peril of COVID-19 PandemicDEBARATI DEB0RUPAM SINHA1SUBHADEEP MAITY2HARSH VARDHAN JHA3Mainak Datta4Postgraduate Trainee, Department of Oral Medicine and Radiology, Haldia Institution of Dental Sciences and Research, Purba Medinipur, West Bengal, India.Professor and Head, Department of Oral Medicine and Radiology, Haldia Institution of Dental Sciences and Research, Purba Medinipur, West Bengal, India.Assistant Professor, Department of Oral Medicine and Radiology, Haldia Institution of Dental Sciences and Research, Purba Medinipur, West Bengal, India.Assistant Professor, Department of Oral Medicine and Radiology, Haldia Institution of Dental Sciences and Research, Purba Medinipur, West Bengal, India.Postgraduate Trainee, Department of Oral Medicine and Radiology, Haldia Institution of Dental Sciences and Research, Purba Medinipur, West Bengal, India.Oral Lichen Planus (OLP) is a chronic autoimmune inflammatory disease of the oral mucosa. The erosive variety of OLP is multifocal, ulcerative, and painful in nature. Patients with OLP have a higher risk of developing Oral Squamous Cell Carcinomas (OSCCs). Here, authors presents a case of 49-year-old female patient presented to the Department of Oral Medicine and Radiology with the chief complaint of burning sensation in the inner aspect of right cheek, since one year. A diffuse whitish area surrounded by erythematous area was present in the right buccal mucosa. Lesion was diagnosed primarily as erosive Lichen Planus (LP). She discontinued the medication and did not come for follow-up visits because of the Coronavirus Disease-2019 (COVID-19) pandemic. After 10 months, she came back with pain and a diffuse swelling with indurated margin in the same region involving right buccal vestibule and retromolar area. After incisional biopsy it was found that the lesion has progressed to squamous cell carcinoma, and the patient was referred to the Department of Oral Surgery where segmental mandibulectomy was done with placement of free fibula graft. The OLP is considered as a potentially malignant disorder and patient should be advised to avoid additional risk factors such as tobacco and alcohol and should be followed at minimum one year interval as prognosis and patient survival is directly related to stage and grade of cancer at its initial diagnosis.https://jcdr.net/articles/PDF/15502/51282_CE[Ra1]_F[SH]_PF1(SC_SS)_PFA_NC_PN(KM).pdfautoimmunebuccal mucosacoronavirus disease-2019oral premalignant disorder |
| spellingShingle | DEBARATI DEB RUPAM SINHA SUBHADEEP MAITY HARSH VARDHAN JHA Mainak Datta Malignant Transformation of Oral Lichen Planus: A Peril of COVID-19 Pandemic Journal of Clinical and Diagnostic Research autoimmune buccal mucosa coronavirus disease-2019 oral premalignant disorder |
| title | Malignant Transformation of Oral Lichen Planus: A Peril of COVID-19 Pandemic |
| title_full | Malignant Transformation of Oral Lichen Planus: A Peril of COVID-19 Pandemic |
| title_fullStr | Malignant Transformation of Oral Lichen Planus: A Peril of COVID-19 Pandemic |
| title_full_unstemmed | Malignant Transformation of Oral Lichen Planus: A Peril of COVID-19 Pandemic |
| title_short | Malignant Transformation of Oral Lichen Planus: A Peril of COVID-19 Pandemic |
| title_sort | malignant transformation of oral lichen planus a peril of covid 19 pandemic |
| topic | autoimmune buccal mucosa coronavirus disease-2019 oral premalignant disorder |
| url | https://jcdr.net/articles/PDF/15502/51282_CE[Ra1]_F[SH]_PF1(SC_SS)_PFA_NC_PN(KM).pdf |
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