Multivalent structure of galectin-1-nanogold complex serves as potential therapeutics for rheumatoid arthritis by enhancing receptor clustering

Multivalent structure of galectin-1-nanogold complex serves as potential therapeutics for rheumatoid arthritis by enhancing receptor clustering

Cellular behaviour is controlled by numerous processes, including intracellular signalling pathways that are triggered by the binding of ligands with cell surface receptors. Multivalent ligands have multiple copies of a recognition element that binds to receptors and influences downstream signals. N...

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Bibliographic Details
Main Authors: Y-J Huang, A-L Shiau, S-Y Chen, Y-L Chen, C-R Wang, C-Y Tsai, M-Y Chang, Y-T Li, C-H Leu, C-L Wu
Format: Article
Language:English
Published: Forum Multimedia Publishing LLC 2012-03-01
Series:European Cells & Materials
Subjects:
Rheumatoid arthritis
ankle joint
apoptosis
cell-surface receptors
galectin-1
gold
inflammation
nanoparticles
Online Access:http://www.ecmjournal.org/journal/papers/vol023/pdf/v023a13.pdf

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