Decoding HiPSC-CM’s Response to SARS-CoV-2: mapping the molecular landscape of cardiac injury

Decoding HiPSC-CM’s Response to SARS-CoV-2: mapping the molecular landscape of cardiac injury

Abstract Background Acute cardiac injury caused by coronavirus disease 2019 (COVID-19) increases mortality. Acute cardiac injury caused by COVID-19 requires understanding how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) directly infects cardiomyocytes. This study provides a solid fou...

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Bibliographic Details
Main Authors: Sicheng Chen, Zhenquan Fu, Kaitong Chen, Xinyao Zheng, Zhenyang Fu
Format: Article
Language:English
Published: BMC 2024-03-01
Series:BMC Genomics
Subjects:
SARS-CoV-2
hiPSC-CMs
Transcriptome analysis
Molecular mechanisms
Biological significance
Mitochondrial dysfunction
Online Access:https://doi.org/10.1186/s12864-024-10194-5

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