Titanium Lattice Structures Produced via Additive Manufacturing for a Bone Scaffold: A Review
The progress in additive manufacturing has remarkably increased the application of lattice materials in the biomedical field for the fabrication of scaffolds used as bone substitutes. Ti6Al4V alloy is widely adopted for bone implant application as it combines both biological and mechanical propertie...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-02-01
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| Series: | Journal of Functional Biomaterials |
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| Online Access: | https://www.mdpi.com/2079-4983/14/3/125 |
| _version_ | 1797610967720263680 |
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| author | Fabio Distefano Salvatore Pasta Gabriella Epasto |
| author_facet | Fabio Distefano Salvatore Pasta Gabriella Epasto |
| author_sort | Fabio Distefano |
| collection | DOAJ |
| description | The progress in additive manufacturing has remarkably increased the application of lattice materials in the biomedical field for the fabrication of scaffolds used as bone substitutes. Ti6Al4V alloy is widely adopted for bone implant application as it combines both biological and mechanical properties. Recent breakthroughs in biomaterials and tissue engineering have allowed the regeneration of massive bone defects, which require external intervention to be bridged. However, the repair of such critical bone defects remains a challenge. The present review collected the most significant findings in the literature of the last ten years on Ti6Al4V porous scaffolds to provide a comprehensive summary of the mechanical and morphological requirements for the osteointegration process. Particular attention was given on the effects of pore size, surface roughness and the elastic modulus on bone scaffold performances. The application of the Gibson–Ashby model allowed for a comparison of the mechanical performance of the lattice materials with that of human bone. This allows for an evaluation of the suitability of different lattice materials for biomedical applications. |
| first_indexed | 2024-03-11T06:21:24Z |
| format | Article |
| id | doaj.art-a879835ade154f2897843bd738559a31 |
| institution | Directory Open Access Journal |
| issn | 2079-4983 |
| language | English |
| last_indexed | 2024-03-11T06:21:24Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Functional Biomaterials |
| spelling | doaj.art-a879835ade154f2897843bd738559a312023-11-17T11:53:56ZengMDPI AGJournal of Functional Biomaterials2079-49832023-02-0114312510.3390/jfb14030125Titanium Lattice Structures Produced via Additive Manufacturing for a Bone Scaffold: A ReviewFabio Distefano0Salvatore Pasta1Gabriella Epasto2Department of Engineering, University of Messina, C.da Di Dio, 98166 Messina, ItalyDepartment of Engineering, University of Palermo, Viale delle Scienze, 90128 Palermo, ItalyDepartment of Engineering, University of Messina, C.da Di Dio, 98166 Messina, ItalyThe progress in additive manufacturing has remarkably increased the application of lattice materials in the biomedical field for the fabrication of scaffolds used as bone substitutes. Ti6Al4V alloy is widely adopted for bone implant application as it combines both biological and mechanical properties. Recent breakthroughs in biomaterials and tissue engineering have allowed the regeneration of massive bone defects, which require external intervention to be bridged. However, the repair of such critical bone defects remains a challenge. The present review collected the most significant findings in the literature of the last ten years on Ti6Al4V porous scaffolds to provide a comprehensive summary of the mechanical and morphological requirements for the osteointegration process. Particular attention was given on the effects of pore size, surface roughness and the elastic modulus on bone scaffold performances. The application of the Gibson–Ashby model allowed for a comparison of the mechanical performance of the lattice materials with that of human bone. This allows for an evaluation of the suitability of different lattice materials for biomedical applications.https://www.mdpi.com/2079-4983/14/3/125lattice structurestitanium alloybone tissue engineeringscaffoldsadditive manufacturingmechanical properties |
| spellingShingle | Fabio Distefano Salvatore Pasta Gabriella Epasto Titanium Lattice Structures Produced via Additive Manufacturing for a Bone Scaffold: A Review Journal of Functional Biomaterials lattice structures titanium alloy bone tissue engineering scaffolds additive manufacturing mechanical properties |
| title | Titanium Lattice Structures Produced via Additive Manufacturing for a Bone Scaffold: A Review |
| title_full | Titanium Lattice Structures Produced via Additive Manufacturing for a Bone Scaffold: A Review |
| title_fullStr | Titanium Lattice Structures Produced via Additive Manufacturing for a Bone Scaffold: A Review |
| title_full_unstemmed | Titanium Lattice Structures Produced via Additive Manufacturing for a Bone Scaffold: A Review |
| title_short | Titanium Lattice Structures Produced via Additive Manufacturing for a Bone Scaffold: A Review |
| title_sort | titanium lattice structures produced via additive manufacturing for a bone scaffold a review |
| topic | lattice structures titanium alloy bone tissue engineering scaffolds additive manufacturing mechanical properties |
| url | https://www.mdpi.com/2079-4983/14/3/125 |
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