What is the point of pseudokinases?
The interaction between an active kinase and an ‘inactive’ pseudokinase provides clues about how these enzymes were regulated in the past, and how this regulation has evolved.
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
eLife Sciences Publications Ltd
2015-05-01
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| Series: | eLife |
| Subjects: | |
| Online Access: | https://elifesciences.org/articles/07771 |
| _version_ | 1828195626969464832 |
|---|---|
| author | Saravanan Raju Andrey S Shaw |
| author_facet | Saravanan Raju Andrey S Shaw |
| author_sort | Saravanan Raju |
| collection | DOAJ |
| description | The interaction between an active kinase and an ‘inactive’ pseudokinase provides clues about how these enzymes were regulated in the past, and how this regulation has evolved. |
| first_indexed | 2024-04-12T09:45:40Z |
| format | Article |
| id | doaj.art-a87988783e8f453a9dab1f197524d4cf |
| institution | Directory Open Access Journal |
| issn | 2050-084X |
| language | English |
| last_indexed | 2024-04-12T09:45:40Z |
| publishDate | 2015-05-01 |
| publisher | eLife Sciences Publications Ltd |
| record_format | Article |
| series | eLife |
| spelling | doaj.art-a87988783e8f453a9dab1f197524d4cf2022-12-22T03:37:57ZengeLife Sciences Publications LtdeLife2050-084X2015-05-01410.7554/eLife.07771What is the point of pseudokinases?Saravanan Raju0Andrey S Shaw1Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, United StatesDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, United StatesThe interaction between an active kinase and an ‘inactive’ pseudokinase provides clues about how these enzymes were regulated in the past, and how this regulation has evolved.https://elifesciences.org/articles/07771kinase complexextracellular protein phosphorylationsecretory pathway phosphorylationpseudokinasetooth enamel formation |
| spellingShingle | Saravanan Raju Andrey S Shaw What is the point of pseudokinases? eLife kinase complex extracellular protein phosphorylation secretory pathway phosphorylation pseudokinase tooth enamel formation |
| title | What is the point of pseudokinases? |
| title_full | What is the point of pseudokinases? |
| title_fullStr | What is the point of pseudokinases? |
| title_full_unstemmed | What is the point of pseudokinases? |
| title_short | What is the point of pseudokinases? |
| title_sort | what is the point of pseudokinases |
| topic | kinase complex extracellular protein phosphorylation secretory pathway phosphorylation pseudokinase tooth enamel formation |
| url | https://elifesciences.org/articles/07771 |
| work_keys_str_mv | AT saravananraju whatisthepointofpseudokinases AT andreysshaw whatisthepointofpseudokinases |