Synthetic Biomimetic Membranes and Their Sensor Applications

Synthetic biomimetic membranes provide biological environments to membrane proteins. By exploiting the central roles of biological membranes, it is possible to devise biosensors, drug delivery systems, and nanocontainers using a biomimetic membrane system integrated with functional proteins. Biomime...

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Main Authors: Young-Rok Kim, Sungho Jung, Hyunil Ryu, Yeong-Eun Yoo, Sun Min Kim, Tae-Joon Jeon
Format: Article
Language:English
Published: MDPI AG 2012-07-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/12/7/9530
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author Young-Rok Kim
Sungho Jung
Hyunil Ryu
Yeong-Eun Yoo
Sun Min Kim
Tae-Joon Jeon
author_facet Young-Rok Kim
Sungho Jung
Hyunil Ryu
Yeong-Eun Yoo
Sun Min Kim
Tae-Joon Jeon
author_sort Young-Rok Kim
collection DOAJ
description Synthetic biomimetic membranes provide biological environments to membrane proteins. By exploiting the central roles of biological membranes, it is possible to devise biosensors, drug delivery systems, and nanocontainers using a biomimetic membrane system integrated with functional proteins. Biomimetic membranes can be created with synthetic lipids or block copolymers. These amphiphilic lipids and polymers self-assemble in an aqueous solution either into planar membranes or into vesicles. Using various techniques developed to date, both planar membranes and vesicles can provide versatile and robust platforms for a number of applications. In particular, biomimetic membranes with modified lipids or functional proteins are promising platforms for biosensors. We review recent technologies used to create synthetic biomimetic membranes and their engineered sensors applications.
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spelling doaj.art-a880bf4beedf441c96c2866d91347a1d2022-12-22T02:20:43ZengMDPI AGSensors1424-82202012-07-011279530955010.3390/s120709530Synthetic Biomimetic Membranes and Their Sensor ApplicationsYoung-Rok KimSungho JungHyunil RyuYeong-Eun YooSun Min KimTae-Joon JeonSynthetic biomimetic membranes provide biological environments to membrane proteins. By exploiting the central roles of biological membranes, it is possible to devise biosensors, drug delivery systems, and nanocontainers using a biomimetic membrane system integrated with functional proteins. Biomimetic membranes can be created with synthetic lipids or block copolymers. These amphiphilic lipids and polymers self-assemble in an aqueous solution either into planar membranes or into vesicles. Using various techniques developed to date, both planar membranes and vesicles can provide versatile and robust platforms for a number of applications. In particular, biomimetic membranes with modified lipids or functional proteins are promising platforms for biosensors. We review recent technologies used to create synthetic biomimetic membranes and their engineered sensors applications.http://www.mdpi.com/1424-8220/12/7/9530biomimetic membraneslipid bilayerion channel sensors
spellingShingle Young-Rok Kim
Sungho Jung
Hyunil Ryu
Yeong-Eun Yoo
Sun Min Kim
Tae-Joon Jeon
Synthetic Biomimetic Membranes and Their Sensor Applications
Sensors
biomimetic membranes
lipid bilayer
ion channel sensors
title Synthetic Biomimetic Membranes and Their Sensor Applications
title_full Synthetic Biomimetic Membranes and Their Sensor Applications
title_fullStr Synthetic Biomimetic Membranes and Their Sensor Applications
title_full_unstemmed Synthetic Biomimetic Membranes and Their Sensor Applications
title_short Synthetic Biomimetic Membranes and Their Sensor Applications
title_sort synthetic biomimetic membranes and their sensor applications
topic biomimetic membranes
lipid bilayer
ion channel sensors
url http://www.mdpi.com/1424-8220/12/7/9530
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