Pathological and histochemical changes in the lungs of rabbits experimentally infected with P.seudomonas aeruginosa

The main objective to this study is to demonstrate certain aspects of pathological and histochomical changes in the lungs of rabbits experimentaly infected with P.aeruginosa .  Twelve white Newzoland rabbits of 12-16 weeks old were used . they were randomaly divided into two groups. The first gro...

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Main Authors: AL. Kutbi, S. H., M. J. Alwan
Format: Article
Language:English
Published: University of Baghdad, College of Veterinary Medicine 2001-06-01
Series:The Iraqi Journal of Veterinary Medicine
Subjects:
Online Access:https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/1144
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author AL. Kutbi, S. H.
M. J. Alwan
author_facet AL. Kutbi, S. H.
M. J. Alwan
author_sort AL. Kutbi, S. H.
collection DOAJ
description The main objective to this study is to demonstrate certain aspects of pathological and histochomical changes in the lungs of rabbits experimentaly infected with P.aeruginosa .  Twelve white Newzoland rabbits of 12-16 weeks old were used . they were randomaly divided into two groups. The first group (6 animals ) were given single intraperitoneal, dose of 108 CFU of P. aeruginosa . The second group (6 animals ) maintained as a control and was inoculated with 1 ml of sterial normal saline by the same route of the first group. All the animals were sacrificed on day three post – inoculation.  The pathological exmination showed acute suppurative reaction in pulmonary tissue together with lymphocytic aggregation around airways and blood vessels. The histochomical study revealed that the granules of goblet cells and submucesal glands of the lung in normal rabbits were of neutral mucopolysaecharides and little sialomucin, these substances changed to sulfated acid mucopolysaccharide and sialomucin in the infected animals.
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spelling doaj.art-a88174ef098f496b95bef13abc6179f52022-12-21T23:28:47ZengUniversity of Baghdad, College of Veterinary MedicineThe Iraqi Journal of Veterinary Medicine1609-56932410-74092001-06-0125110.30539/ijvm.v25i1.1144Pathological and histochemical changes in the lungs of rabbits experimentally infected with P.seudomonas aeruginosaAL. Kutbi, S. H.0M. J. Alwan1Dept. of Vet. Pathology and Poultry, College of Vet. Med. University of Baghdad, Iraq.Dept. of Vet. Pathology and Poultry, College of Vet. Med. University of Baghdad, Iraq.The main objective to this study is to demonstrate certain aspects of pathological and histochomical changes in the lungs of rabbits experimentaly infected with P.aeruginosa .  Twelve white Newzoland rabbits of 12-16 weeks old were used . they were randomaly divided into two groups. The first group (6 animals ) were given single intraperitoneal, dose of 108 CFU of P. aeruginosa . The second group (6 animals ) maintained as a control and was inoculated with 1 ml of sterial normal saline by the same route of the first group. All the animals were sacrificed on day three post – inoculation.  The pathological exmination showed acute suppurative reaction in pulmonary tissue together with lymphocytic aggregation around airways and blood vessels. The histochomical study revealed that the granules of goblet cells and submucesal glands of the lung in normal rabbits were of neutral mucopolysaecharides and little sialomucin, these substances changed to sulfated acid mucopolysaccharide and sialomucin in the infected animals.https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/1144rabbitsPathologicalhistochemicalP.seudomonas
spellingShingle AL. Kutbi, S. H.
M. J. Alwan
Pathological and histochemical changes in the lungs of rabbits experimentally infected with P.seudomonas aeruginosa
The Iraqi Journal of Veterinary Medicine
rabbits
Pathological
histochemical
P.seudomonas
title Pathological and histochemical changes in the lungs of rabbits experimentally infected with P.seudomonas aeruginosa
title_full Pathological and histochemical changes in the lungs of rabbits experimentally infected with P.seudomonas aeruginosa
title_fullStr Pathological and histochemical changes in the lungs of rabbits experimentally infected with P.seudomonas aeruginosa
title_full_unstemmed Pathological and histochemical changes in the lungs of rabbits experimentally infected with P.seudomonas aeruginosa
title_short Pathological and histochemical changes in the lungs of rabbits experimentally infected with P.seudomonas aeruginosa
title_sort pathological and histochemical changes in the lungs of rabbits experimentally infected with p seudomonas aeruginosa
topic rabbits
Pathological
histochemical
P.seudomonas
url https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/1144
work_keys_str_mv AT alkutbish pathologicalandhistochemicalchangesinthelungsofrabbitsexperimentallyinfectedwithpseudomonasaeruginosa
AT mjalwan pathologicalandhistochemicalchangesinthelungsofrabbitsexperimentallyinfectedwithpseudomonasaeruginosa