Joint use of microwave and glycerol-zinc (II) acetate catalytic system in the synthesis of 2-pyridyl-2-oxazolines
Glycerol combined with zinc (II) acetate catalyzed the reaction of 2-amino alcohols and 2-cyanopyridines under microwave irradiation, resulting in 2-pyridyl-2-oxazolines. Comparing the conversion to that obtained by conventional heating, a significant decrease in the reaction time was achieved. At t...
| المؤلفون الرئيسيون: | , , , , |
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| التنسيق: | مقال |
| اللغة: | English |
| منشور في: |
De Gruyter
2013-02-01
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| سلاسل: | Green Processing and Synthesis |
| الموضوعات: | |
| الوصول للمادة أونلاين: | https://doi.org/10.1515/gps-2012-0085 |
| الملخص: | Glycerol combined with zinc (II) acetate catalyzed the reaction of 2-amino alcohols and 2-cyanopyridines under microwave irradiation, resulting in 2-pyridyl-2-oxazolines. Comparing the conversion to that obtained by conventional heating, a significant decrease in the reaction time was achieved. At the end of the reaction, the product was isolated and the glycerol-zinc (II) acetate catalytic system was recycled four times for the same transformation in reasonable to acceptable yields. The products were obtained in their pure form by simple filtration in a short pad of silica. |
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| تدمد: | 2191-9542 2191-9550 |