Senescent Fibroblasts Generate a CAF Phenotype through the Stat3 Pathway

Senescent Fibroblasts Generate a CAF Phenotype through the Stat3 Pathway

Aging has been recently reported to promote lung cancer initiation and progression. Senescent fibroblasts gain a cancer-associated fibroblast (CAF) phenotype, and exert a powerful influence on cancer behavior, such as tumor cell growth and metastasis. However, mechanisms linking fibroblast senescenc...

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Bibliographic Details
Main Authors: Hao Li, Lei Qiu, Qing Liu, Zelong Ma, Xiaoli Xie, Ying Luo, Xiaoming Wu
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Genes
Subjects:
fibroblast senescence
Stat3 pathway
cancer-associated fibroblasts
Online Access:https://www.mdpi.com/2073-4425/13/9/1579

Internet

https://www.mdpi.com/2073-4425/13/9/1579

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