Obese rats exhibit high levels of fat necrosis and isoprostanes in taurocholate-induced acute pancreatitis.

BACKGROUND: Obesity is a prognostic factor for severity in acute pancreatitis in humans. Our aim was to assess the role of oxidative stress and abdominal fat in the increased severity of acute pancreatitis in obese rats. METHODOLOGY: Taurocholate-induced acute pancreatitis was performed in lean and...

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Bibliographic Details
Main Authors: Javier Pereda, Salvador Pérez, Javier Escobar, Alessandro Arduini, Miguel Asensi, Gaetano Serviddio, Luis Sabater, Luis Aparisi, Juan Sastre
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3445528?pdf=render