The Proportion of Orthostatic Hypotension and Its Relationship with HbA1c Levels in Elderly Patients with Diabetes
Aim: to obtain information on the proportion of orthostatic hypotension in elderly patients with diabetes and its relationship with HbA1c levels. Methods: this is a cross-sectional study on 350 patients with diabetes mellitus (DM) aged ≥60 years old who sought treatment at outpatient clinic of Geria...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Interna Publishing
2016-09-01
|
| Series: | Acta Medica Indonesiana |
| Subjects: | |
| Online Access: | http://www.actamedindones.org/index.php/ijim/article/view/150 |
| _version_ | 1811235029101051904 |
|---|---|
| author | Catarina Budyono Siti Setiati Dyah Purnamasari Cleopas M Rumende |
| author_facet | Catarina Budyono Siti Setiati Dyah Purnamasari Cleopas M Rumende |
| author_sort | Catarina Budyono |
| collection | DOAJ |
| description | Aim: to obtain information on the proportion of orthostatic hypotension in elderly patients with diabetes and its relationship with HbA1c levels. Methods: this is a cross-sectional study on 350 patients with diabetes mellitus (DM) aged ≥60 years old who sought treatment at outpatient clinic of Geriatry and Diabetes Division at Cipto Mangunkusumo Hospital between January and March 2016. Orthostatic hypotension was defined as a decrease in systolic blood pressure ≥20 mmHg and/or diastolic pressure ≥10 mmHg within 3 minutes after changing position from lying to standing. HbA1c levels was measured using Nycocard from Axis Shield. Chi square test was used for bivariate analysis and logistic regression was used for multivariate analysis against confounding variables. Results: the proportion of orthostatic hypotension in elderly subjects with DM was 27.4%. Median of HbA1c levels was higher in subjects with than without orthostatic hypotension (7.6% vs. 7.1%; p<0.05). There was an association between HbA1c levels of ≥7.35% and the incidence of orthostatic hypotension (OR 1.987, 95% CI 1.2-3.2). The duration of having DM was a confounding variable. Conclusion: orthostatic hypotension is more common in elderly subjects with DM. There is an association between the incidence of orthostatic hypotension and increased HbA1c levels in elderly patients with diabetes mellitus. |
| first_indexed | 2024-04-12T11:45:22Z |
| format | Article |
| id | doaj.art-a88ab705f5834e64af732cf0bc518091 |
| institution | Directory Open Access Journal |
| issn | 0125-9326 2338-2732 |
| language | English |
| last_indexed | 2024-04-12T11:45:22Z |
| publishDate | 2016-09-01 |
| publisher | Interna Publishing |
| record_format | Article |
| series | Acta Medica Indonesiana |
| spelling | doaj.art-a88ab705f5834e64af732cf0bc5180912022-12-22T03:34:22ZengInterna PublishingActa Medica Indonesiana0125-93262338-27322016-09-01482147The Proportion of Orthostatic Hypotension and Its Relationship with HbA1c Levels in Elderly Patients with DiabetesCatarina Budyono0Siti Setiati1Dyah Purnamasari2Cleopas M Rumende3Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, IndonesiaDivision of Geriatrics, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital. Jakarta, IndonesiaDivision of Endocrinology and Metaboism, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital. Jakarta, IndonesiaDepartment of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, IndonesiaAim: to obtain information on the proportion of orthostatic hypotension in elderly patients with diabetes and its relationship with HbA1c levels. Methods: this is a cross-sectional study on 350 patients with diabetes mellitus (DM) aged ≥60 years old who sought treatment at outpatient clinic of Geriatry and Diabetes Division at Cipto Mangunkusumo Hospital between January and March 2016. Orthostatic hypotension was defined as a decrease in systolic blood pressure ≥20 mmHg and/or diastolic pressure ≥10 mmHg within 3 minutes after changing position from lying to standing. HbA1c levels was measured using Nycocard from Axis Shield. Chi square test was used for bivariate analysis and logistic regression was used for multivariate analysis against confounding variables. Results: the proportion of orthostatic hypotension in elderly subjects with DM was 27.4%. Median of HbA1c levels was higher in subjects with than without orthostatic hypotension (7.6% vs. 7.1%; p<0.05). There was an association between HbA1c levels of ≥7.35% and the incidence of orthostatic hypotension (OR 1.987, 95% CI 1.2-3.2). The duration of having DM was a confounding variable. Conclusion: orthostatic hypotension is more common in elderly subjects with DM. There is an association between the incidence of orthostatic hypotension and increased HbA1c levels in elderly patients with diabetes mellitus.http://www.actamedindones.org/index.php/ijim/article/view/150diabetes mellituselderlyHbA1corthostatic hypotension |
| spellingShingle | Catarina Budyono Siti Setiati Dyah Purnamasari Cleopas M Rumende The Proportion of Orthostatic Hypotension and Its Relationship with HbA1c Levels in Elderly Patients with Diabetes Acta Medica Indonesiana diabetes mellitus elderly HbA1c orthostatic hypotension |
| title | The Proportion of Orthostatic Hypotension and Its Relationship with HbA1c Levels in Elderly Patients with Diabetes |
| title_full | The Proportion of Orthostatic Hypotension and Its Relationship with HbA1c Levels in Elderly Patients with Diabetes |
| title_fullStr | The Proportion of Orthostatic Hypotension and Its Relationship with HbA1c Levels in Elderly Patients with Diabetes |
| title_full_unstemmed | The Proportion of Orthostatic Hypotension and Its Relationship with HbA1c Levels in Elderly Patients with Diabetes |
| title_short | The Proportion of Orthostatic Hypotension and Its Relationship with HbA1c Levels in Elderly Patients with Diabetes |
| title_sort | proportion of orthostatic hypotension and its relationship with hba1c levels in elderly patients with diabetes |
| topic | diabetes mellitus elderly HbA1c orthostatic hypotension |
| url | http://www.actamedindones.org/index.php/ijim/article/view/150 |
| work_keys_str_mv | AT catarinabudyono theproportionoforthostatichypotensionanditsrelationshipwithhba1clevelsinelderlypatientswithdiabetes AT sitisetiati theproportionoforthostatichypotensionanditsrelationshipwithhba1clevelsinelderlypatientswithdiabetes AT dyahpurnamasari theproportionoforthostatichypotensionanditsrelationshipwithhba1clevelsinelderlypatientswithdiabetes AT cleopasmrumende theproportionoforthostatichypotensionanditsrelationshipwithhba1clevelsinelderlypatientswithdiabetes AT catarinabudyono proportionoforthostatichypotensionanditsrelationshipwithhba1clevelsinelderlypatientswithdiabetes AT sitisetiati proportionoforthostatichypotensionanditsrelationshipwithhba1clevelsinelderlypatientswithdiabetes AT dyahpurnamasari proportionoforthostatichypotensionanditsrelationshipwithhba1clevelsinelderlypatientswithdiabetes AT cleopasmrumende proportionoforthostatichypotensionanditsrelationshipwithhba1clevelsinelderlypatientswithdiabetes |