Progress on application of dipeptidyl peptidase Ⅲ in the treatment of sepsis
Sepsis is still one of the important challenges of medicine in the 21st century. Dipeptide peptidase Ⅲ(DPP3)is a new biomarker associated with sepsis, which mainly degrades angiotensin Ⅱ in human body. It can not only inhibit cardiac systolic function, but also reduce vascular tension, resulting in...
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| Format: | Article |
| Language: | zho |
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Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
2023-01-01
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| Series: | Jichu yixue yu linchuang |
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| Online Access: | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2023-43-1-196.pdf |
| _version_ | 1827391063339302912 |
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| author | WANG Yingchen, SUN Liqun |
| author_facet | WANG Yingchen, SUN Liqun |
| author_sort | WANG Yingchen, SUN Liqun |
| collection | DOAJ |
| description | Sepsis is still one of the important challenges of medicine in the 21st century. Dipeptide peptidase Ⅲ(DPP3)is a new biomarker associated with sepsis, which mainly degrades angiotensin Ⅱ in human body. It can not only inhibit cardiac systolic function, but also reduce vascular tension, resulting in insufficient cardiac output and low blood pressure, resulting in shock and multiple organ dysfunctions in patients with sepsis. Therefore, DPP3 may become a new target for sepsis treatment. |
| first_indexed | 2024-03-08T17:03:15Z |
| format | Article |
| id | doaj.art-a8944ad6abeb4e37a9eaf2637b52ac07 |
| institution | Directory Open Access Journal |
| issn | 1001-6325 |
| language | zho |
| last_indexed | 2024-03-08T17:03:15Z |
| publishDate | 2023-01-01 |
| publisher | Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. |
| record_format | Article |
| series | Jichu yixue yu linchuang |
| spelling | doaj.art-a8944ad6abeb4e37a9eaf2637b52ac072024-01-04T07:27:26ZzhoInstitute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.Jichu yixue yu linchuang1001-63252023-01-0143119619910.16352/j.issn.1001-6325.2023.01.0196Progress on application of dipeptidyl peptidase Ⅲ in the treatment of sepsisWANG Yingchen, SUN Liqun0Intensive Care Unit,the Second Affiliated Hospital of Nanjing Medical University,Nanjing 210000, ChinaSepsis is still one of the important challenges of medicine in the 21st century. Dipeptide peptidase Ⅲ(DPP3)is a new biomarker associated with sepsis, which mainly degrades angiotensin Ⅱ in human body. It can not only inhibit cardiac systolic function, but also reduce vascular tension, resulting in insufficient cardiac output and low blood pressure, resulting in shock and multiple organ dysfunctions in patients with sepsis. Therefore, DPP3 may become a new target for sepsis treatment.http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2023-43-1-196.pdfsepsis|septic shock|dipeptidyl peptidase ⅲ(dpp3)|heart failure |
| spellingShingle | WANG Yingchen, SUN Liqun Progress on application of dipeptidyl peptidase Ⅲ in the treatment of sepsis Jichu yixue yu linchuang sepsis|septic shock|dipeptidyl peptidase ⅲ(dpp3)|heart failure |
| title | Progress on application of dipeptidyl peptidase Ⅲ in the treatment of sepsis |
| title_full | Progress on application of dipeptidyl peptidase Ⅲ in the treatment of sepsis |
| title_fullStr | Progress on application of dipeptidyl peptidase Ⅲ in the treatment of sepsis |
| title_full_unstemmed | Progress on application of dipeptidyl peptidase Ⅲ in the treatment of sepsis |
| title_short | Progress on application of dipeptidyl peptidase Ⅲ in the treatment of sepsis |
| title_sort | progress on application of dipeptidyl peptidase iii in the treatment of sepsis |
| topic | sepsis|septic shock|dipeptidyl peptidase ⅲ(dpp3)|heart failure |
| url | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2023-43-1-196.pdf |
| work_keys_str_mv | AT wangyingchensunliqun progressonapplicationofdipeptidylpeptidaseiiiinthetreatmentofsepsis |