Researching progress on bio-reactive electrogenic materials with electrophysiological activity for enhanced bone regeneration
Bone tissues are dynamically reconstructed during the entire life cycle phase, which is an exquisitely regulated process controlled by intracellular and intercellular signals transmitted through physicochemical and biochemical stimulation. Recently, the role of electrical activity in promoting bone...
| Asıl Yazarlar: | , , , , , , , , |
|---|---|
| Materyal Türü: | Makale |
| Dil: | English |
| Baskı/Yayın Bilgisi: |
Frontiers Media S.A.
2022-07-01
|
| Seri Bilgileri: | Frontiers in Bioengineering and Biotechnology |
| Konular: | |
| Online Erişim: | https://www.frontiersin.org/articles/10.3389/fbioe.2022.921284/full |
| _version_ | 1828785394236260352 |
|---|---|
| author | Shaojie Dong Shaojie Dong Shaojie Dong Yuwei Zhang Yuwei Zhang Yukun Mei Yukun Mei Yifei Zhang Yifei Zhang Yaqi Hao Yaqi Hao Yaqi Hao Beilei Liang Beilei Liang Beilei Liang Weijiang Dong Rui Zou Rui Zou Lin Niu Lin Niu Lin Niu |
| author_facet | Shaojie Dong Shaojie Dong Shaojie Dong Yuwei Zhang Yuwei Zhang Yukun Mei Yukun Mei Yifei Zhang Yifei Zhang Yaqi Hao Yaqi Hao Yaqi Hao Beilei Liang Beilei Liang Beilei Liang Weijiang Dong Rui Zou Rui Zou Lin Niu Lin Niu Lin Niu |
| author_sort | Shaojie Dong |
| collection | DOAJ |
| description | Bone tissues are dynamically reconstructed during the entire life cycle phase, which is an exquisitely regulated process controlled by intracellular and intercellular signals transmitted through physicochemical and biochemical stimulation. Recently, the role of electrical activity in promoting bone regeneration has attracted great attention, making the design, fabrication, and selection of bioelectric bio-reactive materials a focus. Under specific conditions, piezoelectric, photoelectric, magnetoelectric, acoustoelectric, and thermoelectric materials can generate bioelectric signals similar to those of natural tissues and stimulate osteogenesis-related signaling pathways to enhance the regeneration of bone defects, which can be used for designing novel smart biological materials for engineering tissue regeneration. However, literature summarizing studies relevant to bioelectric materials for bone regeneration is rare to our knowledge. Consequently, this review is mainly focused on the biological mechanism of electrical stimulation in the regeneration of bone defects, the current state and future prospects of piezoelectric materials, and other bioelectric active materials suitable for bone tissue engineering in recent studies, aiming to provide a theoretical basis for novel clinical treatment strategies for bone defects. |
| first_indexed | 2024-12-11T23:50:18Z |
| format | Article |
| id | doaj.art-a89502f1c67a44f687c7826e6fc7d88f |
| institution | Directory Open Access Journal |
| issn | 2296-4185 |
| language | English |
| last_indexed | 2024-12-11T23:50:18Z |
| publishDate | 2022-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj.art-a89502f1c67a44f687c7826e6fc7d88f2022-12-22T00:45:29ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852022-07-011010.3389/fbioe.2022.921284921284Researching progress on bio-reactive electrogenic materials with electrophysiological activity for enhanced bone regenerationShaojie Dong0Shaojie Dong1Shaojie Dong2Yuwei Zhang3Yuwei Zhang4Yukun Mei5Yukun Mei6Yifei Zhang7Yifei Zhang8Yaqi Hao9Yaqi Hao10Yaqi Hao11Beilei Liang12Beilei Liang13Beilei Liang14Weijiang Dong15Rui Zou16Rui Zou17Lin Niu18Lin Niu19Lin Niu20Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi’an Jiaotong University, Xi’an, ChinaClinical Research Center of Shaanxi Province for Dental and Maxillofacial Diseases, Xi’an, ChinaDepartment of Prosthodontics, College of Stomatology, Xi’an Jiaotong University, Xi’an, ChinaKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi’an Jiaotong University, Xi’an, ChinaClinical Research Center of Shaanxi Province for Dental and Maxillofacial Diseases, Xi’an, ChinaKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi’an Jiaotong University, Xi’an, ChinaClinical Research Center of Shaanxi Province for Dental and Maxillofacial Diseases, Xi’an, ChinaKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi’an Jiaotong University, Xi’an, ChinaClinical Research Center of Shaanxi Province for Dental and Maxillofacial Diseases, Xi’an, ChinaKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi’an Jiaotong University, Xi’an, ChinaClinical Research Center of Shaanxi Province for Dental and Maxillofacial Diseases, Xi’an, ChinaDepartment of Prosthodontics, College of Stomatology, Xi’an Jiaotong University, Xi’an, ChinaKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi’an Jiaotong University, Xi’an, ChinaClinical Research Center of Shaanxi Province for Dental and Maxillofacial Diseases, Xi’an, ChinaDepartment of Prosthodontics, College of Stomatology, Xi’an Jiaotong University, Xi’an, ChinaSchool of Basic Sciences of Xi’an Jiaotong University Health Science Center, Xi’an, ChinaKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi’an Jiaotong University, Xi’an, ChinaClinical Research Center of Shaanxi Province for Dental and Maxillofacial Diseases, Xi’an, ChinaKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi’an Jiaotong University, Xi’an, ChinaClinical Research Center of Shaanxi Province for Dental and Maxillofacial Diseases, Xi’an, ChinaDepartment of Prosthodontics, College of Stomatology, Xi’an Jiaotong University, Xi’an, ChinaBone tissues are dynamically reconstructed during the entire life cycle phase, which is an exquisitely regulated process controlled by intracellular and intercellular signals transmitted through physicochemical and biochemical stimulation. Recently, the role of electrical activity in promoting bone regeneration has attracted great attention, making the design, fabrication, and selection of bioelectric bio-reactive materials a focus. Under specific conditions, piezoelectric, photoelectric, magnetoelectric, acoustoelectric, and thermoelectric materials can generate bioelectric signals similar to those of natural tissues and stimulate osteogenesis-related signaling pathways to enhance the regeneration of bone defects, which can be used for designing novel smart biological materials for engineering tissue regeneration. However, literature summarizing studies relevant to bioelectric materials for bone regeneration is rare to our knowledge. Consequently, this review is mainly focused on the biological mechanism of electrical stimulation in the regeneration of bone defects, the current state and future prospects of piezoelectric materials, and other bioelectric active materials suitable for bone tissue engineering in recent studies, aiming to provide a theoretical basis for novel clinical treatment strategies for bone defects.https://www.frontiersin.org/articles/10.3389/fbioe.2022.921284/fullelectrogenesisbone regenerationelectrical stimulationbio-reactive materialelectrophysiological activity |
| spellingShingle | Shaojie Dong Shaojie Dong Shaojie Dong Yuwei Zhang Yuwei Zhang Yukun Mei Yukun Mei Yifei Zhang Yifei Zhang Yaqi Hao Yaqi Hao Yaqi Hao Beilei Liang Beilei Liang Beilei Liang Weijiang Dong Rui Zou Rui Zou Lin Niu Lin Niu Lin Niu Researching progress on bio-reactive electrogenic materials with electrophysiological activity for enhanced bone regeneration Frontiers in Bioengineering and Biotechnology electrogenesis bone regeneration electrical stimulation bio-reactive material electrophysiological activity |
| title | Researching progress on bio-reactive electrogenic materials with electrophysiological activity for enhanced bone regeneration |
| title_full | Researching progress on bio-reactive electrogenic materials with electrophysiological activity for enhanced bone regeneration |
| title_fullStr | Researching progress on bio-reactive electrogenic materials with electrophysiological activity for enhanced bone regeneration |
| title_full_unstemmed | Researching progress on bio-reactive electrogenic materials with electrophysiological activity for enhanced bone regeneration |
| title_short | Researching progress on bio-reactive electrogenic materials with electrophysiological activity for enhanced bone regeneration |
| title_sort | researching progress on bio reactive electrogenic materials with electrophysiological activity for enhanced bone regeneration |
| topic | electrogenesis bone regeneration electrical stimulation bio-reactive material electrophysiological activity |
| url | https://www.frontiersin.org/articles/10.3389/fbioe.2022.921284/full |
| work_keys_str_mv | AT shaojiedong researchingprogressonbioreactiveelectrogenicmaterialswithelectrophysiologicalactivityforenhancedboneregeneration AT shaojiedong researchingprogressonbioreactiveelectrogenicmaterialswithelectrophysiologicalactivityforenhancedboneregeneration AT shaojiedong researchingprogressonbioreactiveelectrogenicmaterialswithelectrophysiologicalactivityforenhancedboneregeneration AT yuweizhang researchingprogressonbioreactiveelectrogenicmaterialswithelectrophysiologicalactivityforenhancedboneregeneration AT yuweizhang researchingprogressonbioreactiveelectrogenicmaterialswithelectrophysiologicalactivityforenhancedboneregeneration AT yukunmei researchingprogressonbioreactiveelectrogenicmaterialswithelectrophysiologicalactivityforenhancedboneregeneration AT yukunmei researchingprogressonbioreactiveelectrogenicmaterialswithelectrophysiologicalactivityforenhancedboneregeneration AT yifeizhang researchingprogressonbioreactiveelectrogenicmaterialswithelectrophysiologicalactivityforenhancedboneregeneration AT yifeizhang researchingprogressonbioreactiveelectrogenicmaterialswithelectrophysiologicalactivityforenhancedboneregeneration AT yaqihao researchingprogressonbioreactiveelectrogenicmaterialswithelectrophysiologicalactivityforenhancedboneregeneration AT yaqihao researchingprogressonbioreactiveelectrogenicmaterialswithelectrophysiologicalactivityforenhancedboneregeneration AT yaqihao researchingprogressonbioreactiveelectrogenicmaterialswithelectrophysiologicalactivityforenhancedboneregeneration AT beileiliang researchingprogressonbioreactiveelectrogenicmaterialswithelectrophysiologicalactivityforenhancedboneregeneration AT beileiliang researchingprogressonbioreactiveelectrogenicmaterialswithelectrophysiologicalactivityforenhancedboneregeneration AT beileiliang researchingprogressonbioreactiveelectrogenicmaterialswithelectrophysiologicalactivityforenhancedboneregeneration AT weijiangdong researchingprogressonbioreactiveelectrogenicmaterialswithelectrophysiologicalactivityforenhancedboneregeneration AT ruizou researchingprogressonbioreactiveelectrogenicmaterialswithelectrophysiologicalactivityforenhancedboneregeneration AT ruizou researchingprogressonbioreactiveelectrogenicmaterialswithelectrophysiologicalactivityforenhancedboneregeneration AT linniu researchingprogressonbioreactiveelectrogenicmaterialswithelectrophysiologicalactivityforenhancedboneregeneration AT linniu researchingprogressonbioreactiveelectrogenicmaterialswithelectrophysiologicalactivityforenhancedboneregeneration AT linniu researchingprogressonbioreactiveelectrogenicmaterialswithelectrophysiologicalactivityforenhancedboneregeneration |