Hepatitis C prevalence in Denmark -an estimate based on multiple national registers

<p>Abstract</p> <p>Background</p> <p>A national survey for chronic hepatitis C has not been performed in Denmark and the prevalence is unknown. Our aim was to estimate the prevalence of chronic hepatitis C from public registers and the proportion of these patients who r...

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Main Authors: Christensen Peer, Hay Gordon, Jepsen Peter, Omland Lars, Just Søren, Krarup Henrik, Weis Nina, Obel Niels, Cowan Susan
Format: Article
Language:English
Published: BMC 2012-08-01
Series:BMC Infectious Diseases
Online Access:http://www.biomedcentral.com/1471-2334/12/178
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author Christensen Peer
Hay Gordon
Jepsen Peter
Omland Lars
Just Søren
Krarup Henrik
Weis Nina
Obel Niels
Cowan Susan
author_facet Christensen Peer
Hay Gordon
Jepsen Peter
Omland Lars
Just Søren
Krarup Henrik
Weis Nina
Obel Niels
Cowan Susan
author_sort Christensen Peer
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>A national survey for chronic hepatitis C has not been performed in Denmark and the prevalence is unknown. Our aim was to estimate the prevalence of chronic hepatitis C from public registers and the proportion of these patients who received specialized healthcare.</p> <p>Methods</p> <p>Patients with a diagnosis of chronic hepatitis C were identified from four national registers: a laboratory register, the Hospital Discharge Register, a clinical database of chronic viral hepatitis and the Register of Communicable Diseases. The total population diagnosed with hepatitis C was estimated by capture-recapture analysis. The population with undiagnosed hepatitis C was derived from the national register of drug users by comparing diagnosed and tested persons.</p> <p>Results</p> <p>A total of 6,935 patients diagnosed with chronic hepatitis C were identified in the four registers and the estimated population diagnosed with the disease was 9,166 persons (95% C.I. interval 8,973 – 9,877), corresponding to 0.21% (95% CI 0.21%-0.23%) of the Danish population over 15years of age. The prevalence was highest among persons 40–49years old (0.39%) and males (0.28%). It was estimated that 40% of the diagnosed patients lived in the capital region, and 33.5% had attended specialised healthcare. It was estimated that 46% of hepatitis C patients had not been diagnosed and the total population with chronic hepatitis C in Denmark was 16,888 (95% C.I. 16,474-18,287), corresponding to 0.38% (95% CI 0.37-0.42) of the population over 15years of age.</p> <p>Conclusions</p> <p>The estimated prevalence of chronic hepatitis C in Denmark was 0.38%. Less than half of the patients with chronic hepatitis C in Denmark have been identified and among these patients, one in three has attended specialised care.</p>
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spelling doaj.art-a899b21d77b947898117efccd90abad82022-12-22T03:00:19ZengBMCBMC Infectious Diseases1471-23342012-08-0112117810.1186/1471-2334-12-178Hepatitis C prevalence in Denmark -an estimate based on multiple national registersChristensen PeerHay GordonJepsen PeterOmland LarsJust SørenKrarup HenrikWeis NinaObel NielsCowan Susan<p>Abstract</p> <p>Background</p> <p>A national survey for chronic hepatitis C has not been performed in Denmark and the prevalence is unknown. Our aim was to estimate the prevalence of chronic hepatitis C from public registers and the proportion of these patients who received specialized healthcare.</p> <p>Methods</p> <p>Patients with a diagnosis of chronic hepatitis C were identified from four national registers: a laboratory register, the Hospital Discharge Register, a clinical database of chronic viral hepatitis and the Register of Communicable Diseases. The total population diagnosed with hepatitis C was estimated by capture-recapture analysis. The population with undiagnosed hepatitis C was derived from the national register of drug users by comparing diagnosed and tested persons.</p> <p>Results</p> <p>A total of 6,935 patients diagnosed with chronic hepatitis C were identified in the four registers and the estimated population diagnosed with the disease was 9,166 persons (95% C.I. interval 8,973 – 9,877), corresponding to 0.21% (95% CI 0.21%-0.23%) of the Danish population over 15years of age. The prevalence was highest among persons 40–49years old (0.39%) and males (0.28%). It was estimated that 40% of the diagnosed patients lived in the capital region, and 33.5% had attended specialised healthcare. It was estimated that 46% of hepatitis C patients had not been diagnosed and the total population with chronic hepatitis C in Denmark was 16,888 (95% C.I. 16,474-18,287), corresponding to 0.38% (95% CI 0.37-0.42) of the population over 15years of age.</p> <p>Conclusions</p> <p>The estimated prevalence of chronic hepatitis C in Denmark was 0.38%. Less than half of the patients with chronic hepatitis C in Denmark have been identified and among these patients, one in three has attended specialised care.</p>http://www.biomedcentral.com/1471-2334/12/178
spellingShingle Christensen Peer
Hay Gordon
Jepsen Peter
Omland Lars
Just Søren
Krarup Henrik
Weis Nina
Obel Niels
Cowan Susan
Hepatitis C prevalence in Denmark -an estimate based on multiple national registers
BMC Infectious Diseases
title Hepatitis C prevalence in Denmark -an estimate based on multiple national registers
title_full Hepatitis C prevalence in Denmark -an estimate based on multiple national registers
title_fullStr Hepatitis C prevalence in Denmark -an estimate based on multiple national registers
title_full_unstemmed Hepatitis C prevalence in Denmark -an estimate based on multiple national registers
title_short Hepatitis C prevalence in Denmark -an estimate based on multiple national registers
title_sort hepatitis c prevalence in denmark an estimate based on multiple national registers
url http://www.biomedcentral.com/1471-2334/12/178
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AT omlandlars hepatitiscprevalenceindenmarkanestimatebasedonmultiplenationalregisters
AT justsøren hepatitiscprevalenceindenmarkanestimatebasedonmultiplenationalregisters
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