Feasibility Study of Microneedle Fabrication from a thin Nitinol Wire Using a CW Single-Mode Fiber Laser
In this paper, feasibility studies are presented on microneedle fabrication by using a multiple-pulse laser microhole drilling technique to drill an axial hole into a thin nitinol wire of 150 μm in diameter. Nitinol is chosen for its biocompatibility and excellent super-elasticity to eliminate break...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2019-06-01
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| Series: | Open Engineering |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/eng-2019-0023 |
| _version_ | 1818677762284584960 |
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| author | Tu Jay Reeves Nicolas |
| author_facet | Tu Jay Reeves Nicolas |
| author_sort | Tu Jay |
| collection | DOAJ |
| description | In this paper, feasibility studies are presented on microneedle fabrication by using a multiple-pulse laser microhole drilling technique to drill an axial hole into a thin nitinol wire of 150 μm in diameter. Nitinol is chosen for its biocompatibility and excellent super-elasticity to eliminate breakage risk. One potential use of this microneedle is for drawing a small amount of blood for glucose monitoring. The critical factor for drilling microholes into a thin nitinol wire axially is the restoration of the semi-infinite material condition, which is the key to prevent the thin wire from being melt away by the laser due to excessive heat transfer in the radial direction. The results show that holes, up to 607 μmin depth, can be drilled into a thin nitinol wire of 150 μm in diameter using 18 repetitions of a 3-pulse group with 13 μs pluses. However, hole quality is poor. The challenges for improving hole qualities, such as centering, hole blockage, through holes, and process parameters, are discussed. |
| first_indexed | 2024-12-17T09:04:31Z |
| format | Article |
| id | doaj.art-a899f455a6494772865cef7d6366858b |
| institution | Directory Open Access Journal |
| issn | 2391-5439 |
| language | English |
| last_indexed | 2024-12-17T09:04:31Z |
| publishDate | 2019-06-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Open Engineering |
| spelling | doaj.art-a899f455a6494772865cef7d6366858b2022-12-21T21:55:35ZengDe GruyterOpen Engineering2391-54392019-06-019116717710.1515/eng-2019-0023eng-2019-0023Feasibility Study of Microneedle Fabrication from a thin Nitinol Wire Using a CW Single-Mode Fiber LaserTu Jay0Reeves Nicolas1Department of Mechanical and Aerospace Engineering, EBIII, North Carolina State University, Raleigh, NC 27695, United States of AmericaDepartment of Mechanical and Aerospace Engineering, EBIII, North Carolina State University, Raleigh, NC 27695, United States of AmericaIn this paper, feasibility studies are presented on microneedle fabrication by using a multiple-pulse laser microhole drilling technique to drill an axial hole into a thin nitinol wire of 150 μm in diameter. Nitinol is chosen for its biocompatibility and excellent super-elasticity to eliminate breakage risk. One potential use of this microneedle is for drawing a small amount of blood for glucose monitoring. The critical factor for drilling microholes into a thin nitinol wire axially is the restoration of the semi-infinite material condition, which is the key to prevent the thin wire from being melt away by the laser due to excessive heat transfer in the radial direction. The results show that holes, up to 607 μmin depth, can be drilled into a thin nitinol wire of 150 μm in diameter using 18 repetitions of a 3-pulse group with 13 μs pluses. However, hole quality is poor. The challenges for improving hole qualities, such as centering, hole blockage, through holes, and process parameters, are discussed.https://doi.org/10.1515/eng-2019-0023microhole drillinglaser drilling laser ablationmicrosecond pulsefiber lasernitinolsuper-elasticitymicroneedle drilling |
| spellingShingle | Tu Jay Reeves Nicolas Feasibility Study of Microneedle Fabrication from a thin Nitinol Wire Using a CW Single-Mode Fiber Laser Open Engineering microhole drilling laser drilling laser ablation microsecond pulse fiber laser nitinol super-elasticity microneedle drilling |
| title | Feasibility Study of Microneedle Fabrication from a thin Nitinol Wire Using a CW Single-Mode Fiber Laser |
| title_full | Feasibility Study of Microneedle Fabrication from a thin Nitinol Wire Using a CW Single-Mode Fiber Laser |
| title_fullStr | Feasibility Study of Microneedle Fabrication from a thin Nitinol Wire Using a CW Single-Mode Fiber Laser |
| title_full_unstemmed | Feasibility Study of Microneedle Fabrication from a thin Nitinol Wire Using a CW Single-Mode Fiber Laser |
| title_short | Feasibility Study of Microneedle Fabrication from a thin Nitinol Wire Using a CW Single-Mode Fiber Laser |
| title_sort | feasibility study of microneedle fabrication from a thin nitinol wire using a cw single mode fiber laser |
| topic | microhole drilling laser drilling laser ablation microsecond pulse fiber laser nitinol super-elasticity microneedle drilling |
| url | https://doi.org/10.1515/eng-2019-0023 |
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