Divergent composition and transposon-silencing activity of small RNAs in mammalian oocytes

Divergent composition and transposon-silencing activity of small RNAs in mammalian oocytes

Abstract Background Small RNAs are essential for germ cell development and fertilization. However, fundamental questions remain, such as the level of conservation in small RNA composition between species and whether small RNAs control transposable elements in mammalian oocytes. Results Here, we use...

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Bibliographic Details
Main Authors: Li Hou, Wei Liu, Hongdao Zhang, Ronghong Li, Miao Liu, Huijuan Shi, Ligang Wu
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Genome Biology
Subjects:
piRNA
PIWI
Transposon
Endo-siRNA
Oocytes
Online Access:https://doi.org/10.1186/s13059-024-03214-w

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