The Atopic March: From Skin to the Airways
Many patients with atopic eczema (AE) would “march” to develop allergic rhinitis (AR) and asthma. Physicians, patients and their families often do not appreciate the significance of these diseases as co-morbidities of atopy. The aim of this study was to evaluate the prevalence and severity of airway...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2012-03-01
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| Series: | Iranian Journal of Allergy, Asthma and Immunology |
| Subjects: | |
| Online Access: | https://ijaai.tums.ac.ir/index.php/ijaai/article/view/333 |
| _version_ | 1818936300537905152 |
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| author | Kam Lun E. Hon Shuxin Susan Wang Ting-fan Leung |
| author_facet | Kam Lun E. Hon Shuxin Susan Wang Ting-fan Leung |
| author_sort | Kam Lun E. Hon |
| collection | DOAJ |
| description | Many patients with atopic eczema (AE) would “march” to develop allergic rhinitis (AR) and asthma. Physicians, patients and their families often do not appreciate the significance of these diseases as co-morbidities of atopy.
The aim of this study was to evaluate the prevalence and severity of airway atopies in patients with AE. AR and asthma severity were assessed in consecutive AE patients seen at a pediatric dermatology clinic by ARS (allergic rhinitis score) and ACT (asthma control test). Eczema severity (SCORAD and Nottingham Eczema Severity Score: NESS) were recorded.
110 patients with AE and 42 patients without AE were recruited. Allergic rhinitis and asthma were significantly more prevalent in patients with AE [odds ratio for AR was 2.9 (CI:1.3 – 6.5) and for asthma 4.3 (CI: 1.3 – 16.10)]. 23 (45%) of the AE patients with AR reported that they were currently on oral antihistamine whereas none of the non-AE group reported such usage. Both groups reported relatively higher sneezing and nasal congestion scores and low “eye watering” score. Comparing mild with moderate-to-severe AE, there was essentially no difference between the prevalence of allergic rhinitis and asthma, or severity of symptoms by ARS and ACT, but females reported more severe symptoms of sneezing and itching nose.
We conclude that allergic disorders of airway are very common among AE patients independent of the eczema severity. Most of the patients have mild-to-moderate AR and asthma. There is a lot of room for parent/patient education, and childhood eczema may prompt early awareness of these airway co-morbidities of atopy. |
| first_indexed | 2024-12-20T05:33:52Z |
| format | Article |
| id | doaj.art-a89d81f15aa9498a83ac18826864acc6 |
| institution | Directory Open Access Journal |
| issn | 1735-1502 1735-5249 |
| language | English |
| last_indexed | 2024-12-20T05:33:52Z |
| publishDate | 2012-03-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Allergy, Asthma and Immunology |
| spelling | doaj.art-a89d81f15aa9498a83ac18826864acc62022-12-21T19:51:41ZengTehran University of Medical SciencesIranian Journal of Allergy, Asthma and Immunology1735-15021735-52492012-03-01111333The Atopic March: From Skin to the AirwaysKam Lun E. Hon0Shuxin Susan Wang1Ting-fan Leung2Department of Pediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, ChinaDepartment of Pediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, ChinaDepartment of Pediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, ChinaMany patients with atopic eczema (AE) would “march” to develop allergic rhinitis (AR) and asthma. Physicians, patients and their families often do not appreciate the significance of these diseases as co-morbidities of atopy. The aim of this study was to evaluate the prevalence and severity of airway atopies in patients with AE. AR and asthma severity were assessed in consecutive AE patients seen at a pediatric dermatology clinic by ARS (allergic rhinitis score) and ACT (asthma control test). Eczema severity (SCORAD and Nottingham Eczema Severity Score: NESS) were recorded. 110 patients with AE and 42 patients without AE were recruited. Allergic rhinitis and asthma were significantly more prevalent in patients with AE [odds ratio for AR was 2.9 (CI:1.3 – 6.5) and for asthma 4.3 (CI: 1.3 – 16.10)]. 23 (45%) of the AE patients with AR reported that they were currently on oral antihistamine whereas none of the non-AE group reported such usage. Both groups reported relatively higher sneezing and nasal congestion scores and low “eye watering” score. Comparing mild with moderate-to-severe AE, there was essentially no difference between the prevalence of allergic rhinitis and asthma, or severity of symptoms by ARS and ACT, but females reported more severe symptoms of sneezing and itching nose. We conclude that allergic disorders of airway are very common among AE patients independent of the eczema severity. Most of the patients have mild-to-moderate AR and asthma. There is a lot of room for parent/patient education, and childhood eczema may prompt early awareness of these airway co-morbidities of atopy.https://ijaai.tums.ac.ir/index.php/ijaai/article/view/333Allergic rhinitisAsthmaAtopic eczemaNESSQuality of lifeSCORAD |
| spellingShingle | Kam Lun E. Hon Shuxin Susan Wang Ting-fan Leung The Atopic March: From Skin to the Airways Iranian Journal of Allergy, Asthma and Immunology Allergic rhinitis Asthma Atopic eczema NESS Quality of life SCORAD |
| title | The Atopic March: From Skin to the Airways |
| title_full | The Atopic March: From Skin to the Airways |
| title_fullStr | The Atopic March: From Skin to the Airways |
| title_full_unstemmed | The Atopic March: From Skin to the Airways |
| title_short | The Atopic March: From Skin to the Airways |
| title_sort | atopic march from skin to the airways |
| topic | Allergic rhinitis Asthma Atopic eczema NESS Quality of life SCORAD |
| url | https://ijaai.tums.ac.ir/index.php/ijaai/article/view/333 |
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