The Physio-Pathological Role of Group I Metabotropic Glutamate Receptors Expressed by Microglia in Health and Disease with a Focus on Amyotrophic Lateral Sclerosis

The Physio-Pathological Role of Group I Metabotropic Glutamate Receptors Expressed by Microglia in Health and Disease with a Focus on Amyotrophic Lateral Sclerosis

Microglia cells are the resident immune cells of the central nervous system. They act as the first-line immune guardians of nervous tissue and central drivers of neuroinflammation. Any homeostatic alteration that can compromise neuron and tissue integrity could activate microglia. Once activated, mi...

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Bibliographic Details
Main Authors:	Matilde Balbi, Giambattista Bonanno, Tiziana Bonifacino, Marco Milanese
Format:	Article
Language:	English
Published:	MDPI AG 2023-03-01
Series:	International Journal of Molecular Sciences
Subjects:	microglia reactive phenotype group I metabotropic glutamate receptors mGlu5 receptor mGlu1 receptor mGluR5
Online Access:	https://www.mdpi.com/1422-0067/24/6/5240

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