Conditionally replicating adenovirus expressing TIMP2 increases survival in a mouse model of disseminated ovarian cancer.
Ovarian cancer remains difficult to treat mainly due to presentation of the disease at an advanced stage. Conditionally-replicating adenoviruses (CRAds) are promising anti-cancer agents that selectively kill the tumor cells. The present study evaluated the efficacy of a novel CRAd (Ad5/3-CXCR4-TIMP2...
| Główni autorzy: | , , , , , , , |
|---|---|
| Format: | Artykuł |
| Język: | English |
| Wydane: |
Public Library of Science (PLoS)
2011-01-01
|
| Seria: | PLoS ONE |
| Dostęp online: | http://europepmc.org/articles/PMC3192051?pdf=render |