Iron salt supplementation during gestation and gestational diabetes mellitus
ABSTRACT OBJETIVE To evaluate the association between the use of iron salts during the first two trimesters of gestation in non-anemic women and the development of gestational diabetes mellitus. METHODS The study used maternal data from the 2015 Pelotas Birth Cohort. All non-anemic women at the...
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| Format: | Article |
| Language: | English |
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Universidade de São Paulo
2023-10-01
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| Series: | Revista de Saúde Pública |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102023000100260&tlng=pt |
| _version_ | 1827786223220948992 |
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| author | Vanessa Iribarrem Avena Miranda Tatiane da Silva Dal Pizzol Marysabel Pinto Telis Silveira Sotero Serrate Mengue Mariângela Freitas da Silveira Bárbara Heather Lutz Andréa Dâmaso Bertoldi |
| author_facet | Vanessa Iribarrem Avena Miranda Tatiane da Silva Dal Pizzol Marysabel Pinto Telis Silveira Sotero Serrate Mengue Mariângela Freitas da Silveira Bárbara Heather Lutz Andréa Dâmaso Bertoldi |
| author_sort | Vanessa Iribarrem Avena Miranda |
| collection | DOAJ |
| description | ABSTRACT OBJETIVE To evaluate the association between the use of iron salts during the first two trimesters of gestation in non-anemic women and the development of gestational diabetes mellitus. METHODS The study used maternal data from the 2015 Pelotas Birth Cohort. All non-anemic women at the 24th week of gestation (n = 2,463) were eligible for this study. Gestational diabetes mellitus was self-reported by women. Crude and adjusted logistic regression were performed considering level of significance = 0.05. RESULTS Among the women studied, 69.7% were exposed to prophylactic iron supplementation in the first two trimesters of gestation. The prevalence of gestational diabetes mellitus among those exposed was 8.7% (95%CI: 7.4–10.1) and 9.3% (95%CI: 7.4–11.6) among those who were not exposed. Iron supplementation was not associated with increased risk of gestational diabetes mellitus in crude (OR = 0.9; 95%CI: 0,7–1,3) and adjusted analysis (OR = 1.1; 95%CI :0,8–1,6). CONCLUSIONS The results suggest that routine iron use in non-anemic pregnant women does not increase the risk of developing gestational diabetes. This evidence supports the existing national and international guidelines, in which prophylactic iron supplementation is recommended for all pregnant women as soon as they initiate antenatal care in order to prevent iron deficiency anemia. |
| first_indexed | 2024-03-11T16:30:25Z |
| format | Article |
| id | doaj.art-a8a22256b7734af7b2cdc188e12feca6 |
| institution | Directory Open Access Journal |
| issn | 1518-8787 |
| language | English |
| last_indexed | 2024-03-11T16:30:25Z |
| publishDate | 2023-10-01 |
| publisher | Universidade de São Paulo |
| record_format | Article |
| series | Revista de Saúde Pública |
| spelling | doaj.art-a8a22256b7734af7b2cdc188e12feca62023-10-24T07:38:27ZengUniversidade de São PauloRevista de Saúde Pública1518-87872023-10-015710.11606/s1518-8787.2023057004871Iron salt supplementation during gestation and gestational diabetes mellitusVanessa Iribarrem Avena Mirandahttps://orcid.org/0000-0002-9156-5036Tatiane da Silva Dal Pizzolhttps://orcid.org/0000-0002-7566-7745Marysabel Pinto Telis Silveirahttps://orcid.org/0000-0002-6453-8534Sotero Serrate Menguehttps://orcid.org/0000-0002-3349-8541Mariângela Freitas da Silveirahttps://orcid.org/0000-0002-1028-2158Bárbara Heather Lutzhttps://orcid.org/0000-0002-9536-1516Andréa Dâmaso Bertoldihttps://orcid.org/0000-0002-4680-3197ABSTRACT OBJETIVE To evaluate the association between the use of iron salts during the first two trimesters of gestation in non-anemic women and the development of gestational diabetes mellitus. METHODS The study used maternal data from the 2015 Pelotas Birth Cohort. All non-anemic women at the 24th week of gestation (n = 2,463) were eligible for this study. Gestational diabetes mellitus was self-reported by women. Crude and adjusted logistic regression were performed considering level of significance = 0.05. RESULTS Among the women studied, 69.7% were exposed to prophylactic iron supplementation in the first two trimesters of gestation. The prevalence of gestational diabetes mellitus among those exposed was 8.7% (95%CI: 7.4–10.1) and 9.3% (95%CI: 7.4–11.6) among those who were not exposed. Iron supplementation was not associated with increased risk of gestational diabetes mellitus in crude (OR = 0.9; 95%CI: 0,7–1,3) and adjusted analysis (OR = 1.1; 95%CI :0,8–1,6). CONCLUSIONS The results suggest that routine iron use in non-anemic pregnant women does not increase the risk of developing gestational diabetes. This evidence supports the existing national and international guidelines, in which prophylactic iron supplementation is recommended for all pregnant women as soon as they initiate antenatal care in order to prevent iron deficiency anemia.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102023000100260&tlng=ptPharmacoepidemiologyDrug UtilizationCohort StudiesDiabetes, Gestational |
| spellingShingle | Vanessa Iribarrem Avena Miranda Tatiane da Silva Dal Pizzol Marysabel Pinto Telis Silveira Sotero Serrate Mengue Mariângela Freitas da Silveira Bárbara Heather Lutz Andréa Dâmaso Bertoldi Iron salt supplementation during gestation and gestational diabetes mellitus Revista de Saúde Pública Pharmacoepidemiology Drug Utilization Cohort Studies Diabetes, Gestational |
| title | Iron salt supplementation during gestation and gestational diabetes mellitus |
| title_full | Iron salt supplementation during gestation and gestational diabetes mellitus |
| title_fullStr | Iron salt supplementation during gestation and gestational diabetes mellitus |
| title_full_unstemmed | Iron salt supplementation during gestation and gestational diabetes mellitus |
| title_short | Iron salt supplementation during gestation and gestational diabetes mellitus |
| title_sort | iron salt supplementation during gestation and gestational diabetes mellitus |
| topic | Pharmacoepidemiology Drug Utilization Cohort Studies Diabetes, Gestational |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102023000100260&tlng=pt |
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