In vivo therapeutic success of MicroRNA-155 antagomir in a mouse model of pulmonary fibrosis induced by bleomycin

In vivo therapeutic success of MicroRNA-155 antagomir in a mouse model of pulmonary fibrosis induced by bleomycin

Background/Aims MicroRNAs (miRNAs) play critical regulatory roles in the pathogenesis of pulmonary fibrosis. The aim of this study was to explore whether miRNA antagomirs could serve as potential therapeutic agents in interstitial lung diseases. Methods A mouse model of pulmonary fibrosis was establ...

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Bibliographic Details
Main Authors: Xiaoyuan Sun, Yu Kang, Shan Xue, Jing Zou, Jiabo Xu, Daoqiang Tang, Hui Qin
Format: Article
Language:English
Published: The Korean Association of Internal Medicine 2021-03-01
Series:The Korean Journal of Internal Medicine
Subjects:
pulmonary fibrosis
microrna-155
antagomir
bleomycin
Online Access:http://www.kjim.org/upload/pdf/kjim-2019-098.pdf

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