A numerical study of COVID-19 epidemic model with vaccination and diffusion

The coronavirus infectious disease (or COVID-19) is a severe respiratory illness. Although the infection incidence decreased significantly, still it remains a major panic for human health and the global economy. The spatial movement of the population from one region to another remains one of the maj...

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Main Authors: Ahmed Alshehri, Saif Ullah
Format: Article
Language:English
Published: AIMS Press 2023-01-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2023215?viewType=HTML
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author Ahmed Alshehri
Saif Ullah
author_facet Ahmed Alshehri
Saif Ullah
author_sort Ahmed Alshehri
collection DOAJ
description The coronavirus infectious disease (or COVID-19) is a severe respiratory illness. Although the infection incidence decreased significantly, still it remains a major panic for human health and the global economy. The spatial movement of the population from one region to another remains one of the major causes of the spread of the infection. In the literature, most of the COVID-19 models have been constructed with only temporal effects. In this paper, a vaccinated spatio-temporal COVID-19 mathematical model is developed to study the impact of vaccines and other interventions on the disease dynamics in a spatially heterogeneous environment. Initially, some of the basic mathematical properties including existence, uniqueness, positivity, and boundedness of the diffusive vaccinated models are analyzed. The model equilibria and the basic reproductive number are presented. Further, based upon the uniform and non-uniform initial conditions, the spatio-temporal COVID-19 mathematical model is solved numerically using finite difference operator-splitting scheme. Furthermore, detailed simulation results are presented in order to visualize the impact of vaccination and other model key parameters with and without diffusion on the pandemic incidence. The obtained results reveal that the suggested intervention with diffusion has a significant impact on the disease dynamics and its control.
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spelling doaj.art-a8a84486021b4dde9ac3defd8981ea982023-02-01T01:42:46ZengAIMS PressMathematical Biosciences and Engineering1551-00182023-01-012034643467210.3934/mbe.2023215A numerical study of COVID-19 epidemic model with vaccination and diffusionAhmed Alshehri0Saif Ullah11. Department of Mathematics, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia2. Department of Mathematics, University of Peshawar, Khyber Pakhtunkhwa, PakistanThe coronavirus infectious disease (or COVID-19) is a severe respiratory illness. Although the infection incidence decreased significantly, still it remains a major panic for human health and the global economy. The spatial movement of the population from one region to another remains one of the major causes of the spread of the infection. In the literature, most of the COVID-19 models have been constructed with only temporal effects. In this paper, a vaccinated spatio-temporal COVID-19 mathematical model is developed to study the impact of vaccines and other interventions on the disease dynamics in a spatially heterogeneous environment. Initially, some of the basic mathematical properties including existence, uniqueness, positivity, and boundedness of the diffusive vaccinated models are analyzed. The model equilibria and the basic reproductive number are presented. Further, based upon the uniform and non-uniform initial conditions, the spatio-temporal COVID-19 mathematical model is solved numerically using finite difference operator-splitting scheme. Furthermore, detailed simulation results are presented in order to visualize the impact of vaccination and other model key parameters with and without diffusion on the pandemic incidence. The obtained results reveal that the suggested intervention with diffusion has a significant impact on the disease dynamics and its control.https://www.aimspress.com/article/doi/10.3934/mbe.2023215?viewType=HTMLspace-time covid-19 transmission modelfinite difference operator-splitting schemeexistence and uniquenessnumerical simulation
spellingShingle Ahmed Alshehri
Saif Ullah
A numerical study of COVID-19 epidemic model with vaccination and diffusion
Mathematical Biosciences and Engineering
space-time covid-19 transmission model
finite difference operator-splitting scheme
existence and uniqueness
numerical simulation
title A numerical study of COVID-19 epidemic model with vaccination and diffusion
title_full A numerical study of COVID-19 epidemic model with vaccination and diffusion
title_fullStr A numerical study of COVID-19 epidemic model with vaccination and diffusion
title_full_unstemmed A numerical study of COVID-19 epidemic model with vaccination and diffusion
title_short A numerical study of COVID-19 epidemic model with vaccination and diffusion
title_sort numerical study of covid 19 epidemic model with vaccination and diffusion
topic space-time covid-19 transmission model
finite difference operator-splitting scheme
existence and uniqueness
numerical simulation
url https://www.aimspress.com/article/doi/10.3934/mbe.2023215?viewType=HTML
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