SYNTHESIS, STRUCTURE AND BIOLOGICAL ACTIVITY OF N(4)-ALLYL-3-THIOSEMICARBAZONES AND THEIR COORDINATION COMPOUNDS WITH SOME 3D METALS
<p>The paper presents a review of different N(4)-allyl-3-thiosemicarbazones and their coordination compounds described in literature. N(4)-allyl-3-thiosemicarbazide can form corresponding thiosemicarbazones with aliphatic, aromatic and heteroaromatic carbonyl compounds. In the presence of tran...
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| Format: | Article |
| Language: | English |
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Moldova State University
2016-02-01
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| Series: | Studia Universitatis Moldaviae: Stiinte reale si ale naturii |
| Subjects: | |
| Online Access: | http://ojs.studiamsu.eu/index.php/real-nature/article/view/305 |
| _version_ | 1811201807357050880 |
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| author | Vasilii GRAUR |
| author_facet | Vasilii GRAUR |
| author_sort | Vasilii GRAUR |
| collection | DOAJ |
| description | <p>The paper presents a review of different N(4)-allyl-3-thiosemicarbazones and their coordination compounds described in literature. N(4)-allyl-3-thiosemicarbazide can form corresponding thiosemicarbazones with aliphatic, aromatic and heteroaromatic carbonyl compounds. In the presence of transitional metal ions they can form coordination compounds of different structures. Both coordination compounds and proligands manifest antitumor, antibacterial, antiviral, and antimalarial activities. Copper(II) coordination compounds with these ligands manifest better antitumor activity than corresponding proligands.</p><p> </p><p><strong>SINTEZA, STRUCTURA ŞI ACTIVITATEA BIOLOGICĂ A N(4)-ALIL-3-TIOSEMICARBAZONELOR ŞI A COMPUŞILOR COORDINATIVI AI UNOR METALE 3D CU ACEŞTI LIGANZI</strong></p><p>Lucrarea prezintă o revistă a N(4)-alil-3-tiosemicarbazonelor şi a compuşilor coordinativi cu aceşti liganzi descrise în literatura de specialitate. N(4)-alil-3-tiosemicarbazida formează tiosemicarbazone cu aldehide şi cetone alifatice, aromatice şi heteroaromatice. În prezenţa ionilor de metale de tranziţie acestea pot forma compuşi coordinativi cu diferite structuri. N(4)-alil-3-tiosemicarbazonele şi compuşii coordinativi manifestă activitate antitumorală, antibacterială, antivirală şi antimalarică. Compuşii coordinativi ai cuprului cu aceşti liganzi manifestă activitate antitumorală sporită în comparaţie cu N(4)-alil-3-tiosemicarbazonele corespunzătoare.</p><p> </p> |
| first_indexed | 2024-04-12T02:28:08Z |
| format | Article |
| id | doaj.art-a8a9eb169fb34262ae77605234a65296 |
| institution | Directory Open Access Journal |
| issn | 1814-3237 1857-498X |
| language | English |
| last_indexed | 2024-04-12T02:28:08Z |
| publishDate | 2016-02-01 |
| publisher | Moldova State University |
| record_format | Article |
| series | Studia Universitatis Moldaviae: Stiinte reale si ale naturii |
| spelling | doaj.art-a8a9eb169fb34262ae77605234a652962022-12-22T03:51:55ZengMoldova State UniversityStudia Universitatis Moldaviae: Stiinte reale si ale naturii1814-32371857-498X2016-02-0106 (86)255SYNTHESIS, STRUCTURE AND BIOLOGICAL ACTIVITY OF N(4)-ALLYL-3-THIOSEMICARBAZONES AND THEIR COORDINATION COMPOUNDS WITH SOME 3D METALSVasilii GRAUR0State University of Moldova<p>The paper presents a review of different N(4)-allyl-3-thiosemicarbazones and their coordination compounds described in literature. N(4)-allyl-3-thiosemicarbazide can form corresponding thiosemicarbazones with aliphatic, aromatic and heteroaromatic carbonyl compounds. In the presence of transitional metal ions they can form coordination compounds of different structures. Both coordination compounds and proligands manifest antitumor, antibacterial, antiviral, and antimalarial activities. Copper(II) coordination compounds with these ligands manifest better antitumor activity than corresponding proligands.</p><p> </p><p><strong>SINTEZA, STRUCTURA ŞI ACTIVITATEA BIOLOGICĂ A N(4)-ALIL-3-TIOSEMICARBAZONELOR ŞI A COMPUŞILOR COORDINATIVI AI UNOR METALE 3D CU ACEŞTI LIGANZI</strong></p><p>Lucrarea prezintă o revistă a N(4)-alil-3-tiosemicarbazonelor şi a compuşilor coordinativi cu aceşti liganzi descrise în literatura de specialitate. N(4)-alil-3-tiosemicarbazida formează tiosemicarbazone cu aldehide şi cetone alifatice, aromatice şi heteroaromatice. În prezenţa ionilor de metale de tranziţie acestea pot forma compuşi coordinativi cu diferite structuri. N(4)-alil-3-tiosemicarbazonele şi compuşii coordinativi manifestă activitate antitumorală, antibacterială, antivirală şi antimalarică. Compuşii coordinativi ai cuprului cu aceşti liganzi manifestă activitate antitumorală sporită în comparaţie cu N(4)-alil-3-tiosemicarbazonele corespunzătoare.</p><p> </p>http://ojs.studiamsu.eu/index.php/real-nature/article/view/305N(4)-allyl-3-thiosemicarbazone, complexes, biological activity |
| spellingShingle | Vasilii GRAUR SYNTHESIS, STRUCTURE AND BIOLOGICAL ACTIVITY OF N(4)-ALLYL-3-THIOSEMICARBAZONES AND THEIR COORDINATION COMPOUNDS WITH SOME 3D METALS Studia Universitatis Moldaviae: Stiinte reale si ale naturii N(4)-allyl-3-thiosemicarbazone, complexes, biological activity |
| title | SYNTHESIS, STRUCTURE AND BIOLOGICAL ACTIVITY OF N(4)-ALLYL-3-THIOSEMICARBAZONES AND THEIR COORDINATION COMPOUNDS WITH SOME 3D METALS |
| title_full | SYNTHESIS, STRUCTURE AND BIOLOGICAL ACTIVITY OF N(4)-ALLYL-3-THIOSEMICARBAZONES AND THEIR COORDINATION COMPOUNDS WITH SOME 3D METALS |
| title_fullStr | SYNTHESIS, STRUCTURE AND BIOLOGICAL ACTIVITY OF N(4)-ALLYL-3-THIOSEMICARBAZONES AND THEIR COORDINATION COMPOUNDS WITH SOME 3D METALS |
| title_full_unstemmed | SYNTHESIS, STRUCTURE AND BIOLOGICAL ACTIVITY OF N(4)-ALLYL-3-THIOSEMICARBAZONES AND THEIR COORDINATION COMPOUNDS WITH SOME 3D METALS |
| title_short | SYNTHESIS, STRUCTURE AND BIOLOGICAL ACTIVITY OF N(4)-ALLYL-3-THIOSEMICARBAZONES AND THEIR COORDINATION COMPOUNDS WITH SOME 3D METALS |
| title_sort | synthesis structure and biological activity of n 4 allyl 3 thiosemicarbazones and their coordination compounds with some 3d metals |
| topic | N(4)-allyl-3-thiosemicarbazone, complexes, biological activity |
| url | http://ojs.studiamsu.eu/index.php/real-nature/article/view/305 |
| work_keys_str_mv | AT vasiliigraur synthesisstructureandbiologicalactivityofn4allyl3thiosemicarbazonesandtheircoordinationcompoundswithsome3dmetals |