Endorectal Ultrasound and Magnetic Resonance Imaging for Rectal Cancer Staging: A Modern Multimodality Approach
Preoperative staging represents a crucial point for the management, type of surgery, and candidacy for neoadjuvant therapy in patient with rectal cancer. The most recent clinical guidelines in oncology recommend an accurate preoperative evaluation in order to address early and advanced tumors to dif...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-02-01
|
| Series: | Journal of Clinical Medicine |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2077-0383/10/4/641 |
| _version_ | 1797413003822366720 |
|---|---|
| author | Alfonso Reginelli Alfredo Clemente Angelo Sangiovanni Valerio Nardone Francesco Selvaggi Guido Sciaudone Fortunato Ciardiello Erika Martinelli Roberto Grassi Salvatore Cappabianca |
| author_facet | Alfonso Reginelli Alfredo Clemente Angelo Sangiovanni Valerio Nardone Francesco Selvaggi Guido Sciaudone Fortunato Ciardiello Erika Martinelli Roberto Grassi Salvatore Cappabianca |
| author_sort | Alfonso Reginelli |
| collection | DOAJ |
| description | Preoperative staging represents a crucial point for the management, type of surgery, and candidacy for neoadjuvant therapy in patient with rectal cancer. The most recent clinical guidelines in oncology recommend an accurate preoperative evaluation in order to address early and advanced tumors to different therapeutic options. In particular, potential pitfalls may occur in the assessment of T3 tumors, which represents the most common stage at diagnosis. The depth of tumor invasion is known to be an important prognostic factor in rectal carcinoma; as a consequence, the T3 imaging classification has a substantial importance for treatment strategy and patient survival. However, the differentiation between tumor invasion of perirectal fat and mesorectal desmoplastic reactions remains a main goal for radiologists. Magnetic resonance imaging (MRI) is actually considered as the best imaging modality for rectal cancer staging. Although the endorectal ultrasound (ERUS) is the preferred staging method for early tumors, it could also be useful in identifying perirectal fat invasion. Moreover, the addiction of diffusion weighted imaging (DWI) improves the diagnostic performance of MRI in rectal cancer staging by adding functional information about rectal tumor and adjacent mesorectal tissues. This study investigated the diagnostic performance of conventional MRI alone, in combination with the DWI technique and ERUS in order to assess the best diagnostic imaging combination for rectal cancer staging. |
| first_indexed | 2024-03-09T05:10:18Z |
| format | Article |
| id | doaj.art-a8ad351bf16048cd8ba241c9abdb50b0 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T05:10:18Z |
| publishDate | 2021-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-a8ad351bf16048cd8ba241c9abdb50b02023-12-03T12:49:56ZengMDPI AGJournal of Clinical Medicine2077-03832021-02-0110464110.3390/jcm10040641Endorectal Ultrasound and Magnetic Resonance Imaging for Rectal Cancer Staging: A Modern Multimodality ApproachAlfonso Reginelli0Alfredo Clemente1Angelo Sangiovanni2Valerio Nardone3Francesco Selvaggi4Guido Sciaudone5Fortunato Ciardiello6Erika Martinelli7Roberto Grassi8Salvatore Cappabianca9Radiology and Radiotherapy Unit, Department of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyRadiology and Radiotherapy Unit, Department of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyRadiology and Radiotherapy Unit, Department of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyUnit of Radiation Oncology, Ospedale del Mare, 80147 Naples, ItalyColorectal Surgery, Department of Advanced Medical and Surgical Sciences, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyColorectal Surgery, Department of Advanced Medical and Surgical Sciences, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyMedical Oncology, Department of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyMedical Oncology, Department of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyRadiology and Radiotherapy Unit, Department of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyRadiology and Radiotherapy Unit, Department of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyPreoperative staging represents a crucial point for the management, type of surgery, and candidacy for neoadjuvant therapy in patient with rectal cancer. The most recent clinical guidelines in oncology recommend an accurate preoperative evaluation in order to address early and advanced tumors to different therapeutic options. In particular, potential pitfalls may occur in the assessment of T3 tumors, which represents the most common stage at diagnosis. The depth of tumor invasion is known to be an important prognostic factor in rectal carcinoma; as a consequence, the T3 imaging classification has a substantial importance for treatment strategy and patient survival. However, the differentiation between tumor invasion of perirectal fat and mesorectal desmoplastic reactions remains a main goal for radiologists. Magnetic resonance imaging (MRI) is actually considered as the best imaging modality for rectal cancer staging. Although the endorectal ultrasound (ERUS) is the preferred staging method for early tumors, it could also be useful in identifying perirectal fat invasion. Moreover, the addiction of diffusion weighted imaging (DWI) improves the diagnostic performance of MRI in rectal cancer staging by adding functional information about rectal tumor and adjacent mesorectal tissues. This study investigated the diagnostic performance of conventional MRI alone, in combination with the DWI technique and ERUS in order to assess the best diagnostic imaging combination for rectal cancer staging.https://www.mdpi.com/2077-0383/10/4/641rectal cancermagnetic resonance imagingendorectal ultrasonographyimagingstaging |
| spellingShingle | Alfonso Reginelli Alfredo Clemente Angelo Sangiovanni Valerio Nardone Francesco Selvaggi Guido Sciaudone Fortunato Ciardiello Erika Martinelli Roberto Grassi Salvatore Cappabianca Endorectal Ultrasound and Magnetic Resonance Imaging for Rectal Cancer Staging: A Modern Multimodality Approach Journal of Clinical Medicine rectal cancer magnetic resonance imaging endorectal ultrasonography imaging staging |
| title | Endorectal Ultrasound and Magnetic Resonance Imaging for Rectal Cancer Staging: A Modern Multimodality Approach |
| title_full | Endorectal Ultrasound and Magnetic Resonance Imaging for Rectal Cancer Staging: A Modern Multimodality Approach |
| title_fullStr | Endorectal Ultrasound and Magnetic Resonance Imaging for Rectal Cancer Staging: A Modern Multimodality Approach |
| title_full_unstemmed | Endorectal Ultrasound and Magnetic Resonance Imaging for Rectal Cancer Staging: A Modern Multimodality Approach |
| title_short | Endorectal Ultrasound and Magnetic Resonance Imaging for Rectal Cancer Staging: A Modern Multimodality Approach |
| title_sort | endorectal ultrasound and magnetic resonance imaging for rectal cancer staging a modern multimodality approach |
| topic | rectal cancer magnetic resonance imaging endorectal ultrasonography imaging staging |
| url | https://www.mdpi.com/2077-0383/10/4/641 |
| work_keys_str_mv | AT alfonsoreginelli endorectalultrasoundandmagneticresonanceimagingforrectalcancerstagingamodernmultimodalityapproach AT alfredoclemente endorectalultrasoundandmagneticresonanceimagingforrectalcancerstagingamodernmultimodalityapproach AT angelosangiovanni endorectalultrasoundandmagneticresonanceimagingforrectalcancerstagingamodernmultimodalityapproach AT valerionardone endorectalultrasoundandmagneticresonanceimagingforrectalcancerstagingamodernmultimodalityapproach AT francescoselvaggi endorectalultrasoundandmagneticresonanceimagingforrectalcancerstagingamodernmultimodalityapproach AT guidosciaudone endorectalultrasoundandmagneticresonanceimagingforrectalcancerstagingamodernmultimodalityapproach AT fortunatociardiello endorectalultrasoundandmagneticresonanceimagingforrectalcancerstagingamodernmultimodalityapproach AT erikamartinelli endorectalultrasoundandmagneticresonanceimagingforrectalcancerstagingamodernmultimodalityapproach AT robertograssi endorectalultrasoundandmagneticresonanceimagingforrectalcancerstagingamodernmultimodalityapproach AT salvatorecappabianca endorectalultrasoundandmagneticresonanceimagingforrectalcancerstagingamodernmultimodalityapproach |