Micronutrients influencing the immune response in leprosy
Leprosy is a chronic infectious disease caused by Mycobacterium leprae, an intracellular bacillus of airborne transmission. The disease affects the skin and peripheral nerves and can cause neurological sequelae. The bacillus multiplies slowly in the host and the disease probably occurs due to malfun...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Arán Ediciones, S. L.
2014-01-01
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| Series: | Nutrición Hospitalaria |
| Subjects: | |
| Online Access: | http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112014000100005&lng=en&tlng=en |
| _version_ | 1819104762597998592 |
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| author | Cecília Maria Passos Vázquez Raquel Simões Mendes Netto Kiriaque Barra Ferreira Barbosa Tatiana Rodrigues de Moura Roque Pacheco de Almeida Malcolm S. Duthie Amelia Ribeiro de Jesus |
| author_facet | Cecília Maria Passos Vázquez Raquel Simões Mendes Netto Kiriaque Barra Ferreira Barbosa Tatiana Rodrigues de Moura Roque Pacheco de Almeida Malcolm S. Duthie Amelia Ribeiro de Jesus |
| author_sort | Cecília Maria Passos Vázquez |
| collection | DOAJ |
| description | Leprosy is a chronic infectious disease caused by Mycobacterium leprae, an intracellular bacillus of airborne transmission. The disease affects the skin and peripheral nerves and can cause neurological sequelae. The bacillus multiplies slowly in the host and the disease probably occurs due to malfunctioning in host immune response. This review addresses the role of some specific micronutrients in the immune response, such as Vitamins A, D, E, C, Zinc and Selenium, detailing their mechanisms of actions in infectious diseases, and in leprosy. The immune response to pathogens releases harmful substances, which lead to tissue damage. This review discusses how a decreased level of antioxidants may contribute to an increased oxidative stress and complications of infectious diseases and leprosy. As the nutrients have a regulatory effect in the innate and adaptative immune responses, a perfect balance in their concentrations is important to improve the immune response against the pathogens. |
| first_indexed | 2024-12-22T02:11:30Z |
| format | Article |
| id | doaj.art-a8af2d208c144bd8836c893957ae1caf |
| institution | Directory Open Access Journal |
| issn | 0212-1611 |
| language | English |
| last_indexed | 2024-12-22T02:11:30Z |
| publishDate | 2014-01-01 |
| publisher | Arán Ediciones, S. L. |
| record_format | Article |
| series | Nutrición Hospitalaria |
| spelling | doaj.art-a8af2d208c144bd8836c893957ae1caf2022-12-21T18:42:22ZengArán Ediciones, S. L.Nutrición Hospitalaria0212-16112014-01-01291263610.3305/nh.2014.29.1.6988S0212-16112014000100005Micronutrients influencing the immune response in leprosyCecília Maria Passos Vázquez0Raquel Simões Mendes Netto1Kiriaque Barra Ferreira Barbosa2Tatiana Rodrigues de Moura3Roque Pacheco de Almeida4Malcolm S. Duthie5Amelia Ribeiro de Jesus6Hospital UniversitárioUniversidade Federal de SergipeUniversidade Federal de SergipeHospital UniversitárioHospital UniversitárioIDRI - Infectious Disease Research InstituteHospital UniversitárioLeprosy is a chronic infectious disease caused by Mycobacterium leprae, an intracellular bacillus of airborne transmission. The disease affects the skin and peripheral nerves and can cause neurological sequelae. The bacillus multiplies slowly in the host and the disease probably occurs due to malfunctioning in host immune response. This review addresses the role of some specific micronutrients in the immune response, such as Vitamins A, D, E, C, Zinc and Selenium, detailing their mechanisms of actions in infectious diseases, and in leprosy. The immune response to pathogens releases harmful substances, which lead to tissue damage. This review discusses how a decreased level of antioxidants may contribute to an increased oxidative stress and complications of infectious diseases and leprosy. As the nutrients have a regulatory effect in the innate and adaptative immune responses, a perfect balance in their concentrations is important to improve the immune response against the pathogens.http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112014000100005&lng=en&tlng=enNutriciónLepraEstrés oxidativo y antioxidantes |
| spellingShingle | Cecília Maria Passos Vázquez Raquel Simões Mendes Netto Kiriaque Barra Ferreira Barbosa Tatiana Rodrigues de Moura Roque Pacheco de Almeida Malcolm S. Duthie Amelia Ribeiro de Jesus Micronutrients influencing the immune response in leprosy Nutrición Hospitalaria Nutrición Lepra Estrés oxidativo y antioxidantes |
| title | Micronutrients influencing the immune response in leprosy |
| title_full | Micronutrients influencing the immune response in leprosy |
| title_fullStr | Micronutrients influencing the immune response in leprosy |
| title_full_unstemmed | Micronutrients influencing the immune response in leprosy |
| title_short | Micronutrients influencing the immune response in leprosy |
| title_sort | micronutrients influencing the immune response in leprosy |
| topic | Nutrición Lepra Estrés oxidativo y antioxidantes |
| url | http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112014000100005&lng=en&tlng=en |
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