Childhood Maltreatment, Mental Well-Being, and Healthy Lifestyle in Patients With Chronic Thromboembolic Pulmonary Hypertension
IntroductionChronic thromboembolic pulmonary hypertension (CTEPH) is a potentially life-threatening condition associated with high morbidity and mortality. However, advances in medical, surgical and interventional treatment have markedly improved the outcome of patients with CTEPH. Additional factor...
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| Format: | Article |
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Frontiers Media S.A.
2022-02-01
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| Series: | Frontiers in Psychiatry |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2022.821468/full |
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| author | Nicole Lepsy Madelaine-Rachel Dering Jan Fuge Tanja Meltendorf Marius M. Hoeper Ivo Heitland Jan C. Kamp Da-Hee Park Manuel J. Richter Henning Gall Hossein A. Ghofrani Hossein A. Ghofrani Dietmar Ellermeier Hans-Dieter Kulla Karen M. Olsson Karen M. Olsson Kai G. Kahl |
| author_facet | Nicole Lepsy Madelaine-Rachel Dering Jan Fuge Tanja Meltendorf Marius M. Hoeper Ivo Heitland Jan C. Kamp Da-Hee Park Manuel J. Richter Henning Gall Hossein A. Ghofrani Hossein A. Ghofrani Dietmar Ellermeier Hans-Dieter Kulla Karen M. Olsson Karen M. Olsson Kai G. Kahl |
| author_sort | Nicole Lepsy |
| collection | DOAJ |
| description | IntroductionChronic thromboembolic pulmonary hypertension (CTEPH) is a potentially life-threatening condition associated with high morbidity and mortality. However, advances in medical, surgical and interventional treatment have markedly improved the outcome of patients with CTEPH. Additional factors potentially influencing quality of life (QoL) and outcome in CTEPH are yet to be defined. Child maltreatment is a major risk factor for unfavorable behavioral, mental as well as physical health outcomes and has been associated with decreased QoL. To date, no study assessed the impact of childhood trauma in patients with CTEPH.MethodsPatients with CTEPH were invited to complete the Childhood Trauma Questionnaire (CTQ). Data were compared to prevalence data from the German population. Mental well-being was assessed using the Hospital Anxiety and Depression Scale (HADS) and quality of life was measured using the WHO Quality of Life Questionnaire (WHOQOL). Furthermore, lifestyle factors and physical health parameters were studied.Logistic regression analysis was used to investigate a possible impact of child maltreatment on markers of disease severity.ResultsOne-hundred and seven patients with CTEPH completed the CTQ. These patients reported higher rates of emotional abuse and physical abuse and emotional neglect compared to the German population while rates of physical neglect and sexual abuse did not differ between patients and German population with prevalence of 20.6% for emotional abuse, 20% for physical abuse, 22% for emotional neglect, 46% for physical neglect, and 6% for sexual abuse in patients with CTEPH. Higher CTQ scores were associated with anxiety symptoms as well as negatively associated with QoL. No direct impact of childhood trauma on CTEPH severity was found.ConclusionWe found a higher rate of child maltreatment in patients with CTEPH in comparison to the German population. Correlations suggest moderate associations between CTQ scores and mental health and QoL. Child maltreatment had no significant impact on disease severity. Further investigation on proper interventions to support affected patients is needed. |
| first_indexed | 2024-12-19T12:38:28Z |
| format | Article |
| id | doaj.art-a8b00dcbca69448583e9954054251d0f |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-12-19T12:38:28Z |
| publishDate | 2022-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-a8b00dcbca69448583e9954054251d0f2022-12-21T20:21:03ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402022-02-011310.3389/fpsyt.2022.821468821468Childhood Maltreatment, Mental Well-Being, and Healthy Lifestyle in Patients With Chronic Thromboembolic Pulmonary HypertensionNicole Lepsy0Madelaine-Rachel Dering1Jan Fuge2Tanja Meltendorf3Marius M. Hoeper4Ivo Heitland5Jan C. Kamp6Da-Hee Park7Manuel J. Richter8Henning Gall9Hossein A. Ghofrani10Hossein A. Ghofrani11Dietmar Ellermeier12Hans-Dieter Kulla13Karen M. Olsson14Karen M. Olsson15Kai G. Kahl16Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, GermanyDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, GermanyDepartment of Respiratory Medicine, Hannover Medical School, German Center for Lung Research (DZL/BREATH), Hannover, GermanyDepartment of Respiratory Medicine, Hannover Medical School, German Center for Lung Research (DZL/BREATH), Hannover, GermanyDepartment of Respiratory Medicine, Hannover Medical School, German Center for Lung Research (DZL/BREATH), Hannover, GermanyDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, GermanyDepartment of Respiratory Medicine, Hannover Medical School, German Center for Lung Research (DZL/BREATH), Hannover, GermanyDepartment of Respiratory Medicine, Hannover Medical School, German Center for Lung Research (DZL/BREATH), Hannover, GermanyDepartment of Internal Medicine, German Center for Lung Research (DZL), Justus Liebig University Giessen, Universities of Gießen and Marburg Lung Center, Giessen, GermanyDepartment of Internal Medicine, German Center for Lung Research (DZL), Justus Liebig University Giessen, Universities of Gießen and Marburg Lung Center, Giessen, GermanyDepartment of Internal Medicine, German Center for Lung Research (DZL), Justus Liebig University Giessen, Universities of Gießen and Marburg Lung Center, Giessen, GermanyDepartment of Pneumology, Kerckhoff Heart, Rheuma and Thoracic Center, German Center for Lung Research, Universities of Giessen and Marburg Lung Center, Bad Nauheim, GermanyPulmonale Hypertonie Selbsthilfe, Bottrop, GermanyPulmonale Hypertonie eV, Rheinstetten, GermanyDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, GermanyDepartment of Respiratory Medicine, Hannover Medical School, German Center for Lung Research (DZL/BREATH), Hannover, GermanyDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, GermanyIntroductionChronic thromboembolic pulmonary hypertension (CTEPH) is a potentially life-threatening condition associated with high morbidity and mortality. However, advances in medical, surgical and interventional treatment have markedly improved the outcome of patients with CTEPH. Additional factors potentially influencing quality of life (QoL) and outcome in CTEPH are yet to be defined. Child maltreatment is a major risk factor for unfavorable behavioral, mental as well as physical health outcomes and has been associated with decreased QoL. To date, no study assessed the impact of childhood trauma in patients with CTEPH.MethodsPatients with CTEPH were invited to complete the Childhood Trauma Questionnaire (CTQ). Data were compared to prevalence data from the German population. Mental well-being was assessed using the Hospital Anxiety and Depression Scale (HADS) and quality of life was measured using the WHO Quality of Life Questionnaire (WHOQOL). Furthermore, lifestyle factors and physical health parameters were studied.Logistic regression analysis was used to investigate a possible impact of child maltreatment on markers of disease severity.ResultsOne-hundred and seven patients with CTEPH completed the CTQ. These patients reported higher rates of emotional abuse and physical abuse and emotional neglect compared to the German population while rates of physical neglect and sexual abuse did not differ between patients and German population with prevalence of 20.6% for emotional abuse, 20% for physical abuse, 22% for emotional neglect, 46% for physical neglect, and 6% for sexual abuse in patients with CTEPH. Higher CTQ scores were associated with anxiety symptoms as well as negatively associated with QoL. No direct impact of childhood trauma on CTEPH severity was found.ConclusionWe found a higher rate of child maltreatment in patients with CTEPH in comparison to the German population. Correlations suggest moderate associations between CTQ scores and mental health and QoL. Child maltreatment had no significant impact on disease severity. Further investigation on proper interventions to support affected patients is needed.https://www.frontiersin.org/articles/10.3389/fpsyt.2022.821468/fullchronic thromboembolic pulmonary hypertensionpulmonary hypertensionchildhood maltreatmentchildhood trauma questionnaireCTQCTEPH |
| spellingShingle | Nicole Lepsy Madelaine-Rachel Dering Jan Fuge Tanja Meltendorf Marius M. Hoeper Ivo Heitland Jan C. Kamp Da-Hee Park Manuel J. Richter Henning Gall Hossein A. Ghofrani Hossein A. Ghofrani Dietmar Ellermeier Hans-Dieter Kulla Karen M. Olsson Karen M. Olsson Kai G. Kahl Childhood Maltreatment, Mental Well-Being, and Healthy Lifestyle in Patients With Chronic Thromboembolic Pulmonary Hypertension Frontiers in Psychiatry chronic thromboembolic pulmonary hypertension pulmonary hypertension childhood maltreatment childhood trauma questionnaire CTQ CTEPH |
| title | Childhood Maltreatment, Mental Well-Being, and Healthy Lifestyle in Patients With Chronic Thromboembolic Pulmonary Hypertension |
| title_full | Childhood Maltreatment, Mental Well-Being, and Healthy Lifestyle in Patients With Chronic Thromboembolic Pulmonary Hypertension |
| title_fullStr | Childhood Maltreatment, Mental Well-Being, and Healthy Lifestyle in Patients With Chronic Thromboembolic Pulmonary Hypertension |
| title_full_unstemmed | Childhood Maltreatment, Mental Well-Being, and Healthy Lifestyle in Patients With Chronic Thromboembolic Pulmonary Hypertension |
| title_short | Childhood Maltreatment, Mental Well-Being, and Healthy Lifestyle in Patients With Chronic Thromboembolic Pulmonary Hypertension |
| title_sort | childhood maltreatment mental well being and healthy lifestyle in patients with chronic thromboembolic pulmonary hypertension |
| topic | chronic thromboembolic pulmonary hypertension pulmonary hypertension childhood maltreatment childhood trauma questionnaire CTQ CTEPH |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2022.821468/full |
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