Role of steroids in critically-ill sepsis patients: a review article and literature to review

Sepsis, a life-threatening condition, commonly affecting critically ill patients, is a major cause of death worldwide. It is thus of great importance to determine the optimum management to cure this condition. This review article summarizes the role and effects of corticosteroids in the treatment of...

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Main Authors: Mohsin Mirza, Maryam Zafar, Mariam Siddiqui, Anum Abbas, Joseph Nahas, Muazzam Mirza, Abubakar Tauseef
Format: Article
Language:English
Published: Greater Baltimore Medical Center 2021-11-01
Series:Journal of Community Hospital Internal Medicine Perspectives
Subjects:
Online Access:http://dx.doi.org/10.1080/20009666.2021.1964164
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author Mohsin Mirza
Maryam Zafar
Mariam Siddiqui
Anum Abbas
Joseph Nahas
Muazzam Mirza
Abubakar Tauseef
author_facet Mohsin Mirza
Maryam Zafar
Mariam Siddiqui
Anum Abbas
Joseph Nahas
Muazzam Mirza
Abubakar Tauseef
author_sort Mohsin Mirza
collection DOAJ
description Sepsis, a life-threatening condition, commonly affecting critically ill patients, is a major cause of death worldwide. It is thus of great importance to determine the optimum management to cure this condition. This review article summarizes the role and effects of corticosteroids in the treatment of sepsis and septic shock, and to determine its mortality benefits. We used PubMed, Google scholar, Scopus, and Embase databases for literature review, and terminologies commonly searched were ‘sepsis’, ‘septic shock’, ‘therapeutic use’ and ‘corticosteroids’. In this review article, we reviewed a total of eight different articles being done in last 10 years, relevant to the clinical outcome and effects of corticosteroids. Among those, two demonstrated improved clinical outcomes, two showed both improved clinical outcomes and decreased mortality, three showed increased adverse effects, and the remaining one showed unequivocal results.
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spelling doaj.art-a8b3ec3e0eb84d48a4acf294d6e93c452023-01-02T01:11:25ZengGreater Baltimore Medical CenterJournal of Community Hospital Internal Medicine Perspectives2000-96662021-11-0111682582910.1080/20009666.2021.19641641964164Role of steroids in critically-ill sepsis patients: a review article and literature to reviewMohsin Mirza0Maryam Zafar1Mariam Siddiqui2Anum Abbas3Joseph Nahas4Muazzam Mirza5Abubakar Tauseef6Creighton University School of MedicineDow University of Health Sciences, DUHSDow University of Health Sciences, DUHSUniversity of Nebraska Medical CenterCreighton University School of MedicineCreighton University School of MedicineCreighton University School of MedicineSepsis, a life-threatening condition, commonly affecting critically ill patients, is a major cause of death worldwide. It is thus of great importance to determine the optimum management to cure this condition. This review article summarizes the role and effects of corticosteroids in the treatment of sepsis and septic shock, and to determine its mortality benefits. We used PubMed, Google scholar, Scopus, and Embase databases for literature review, and terminologies commonly searched were ‘sepsis’, ‘septic shock’, ‘therapeutic use’ and ‘corticosteroids’. In this review article, we reviewed a total of eight different articles being done in last 10 years, relevant to the clinical outcome and effects of corticosteroids. Among those, two demonstrated improved clinical outcomes, two showed both improved clinical outcomes and decreased mortality, three showed increased adverse effects, and the remaining one showed unequivocal results.http://dx.doi.org/10.1080/20009666.2021.1964164rolesteroidsepsisreviewliteraurecritically ill
spellingShingle Mohsin Mirza
Maryam Zafar
Mariam Siddiqui
Anum Abbas
Joseph Nahas
Muazzam Mirza
Abubakar Tauseef
Role of steroids in critically-ill sepsis patients: a review article and literature to review
Journal of Community Hospital Internal Medicine Perspectives
role
steroid
sepsis
review
literaure
critically ill
title Role of steroids in critically-ill sepsis patients: a review article and literature to review
title_full Role of steroids in critically-ill sepsis patients: a review article and literature to review
title_fullStr Role of steroids in critically-ill sepsis patients: a review article and literature to review
title_full_unstemmed Role of steroids in critically-ill sepsis patients: a review article and literature to review
title_short Role of steroids in critically-ill sepsis patients: a review article and literature to review
title_sort role of steroids in critically ill sepsis patients a review article and literature to review
topic role
steroid
sepsis
review
literaure
critically ill
url http://dx.doi.org/10.1080/20009666.2021.1964164
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