Role of steroids in critically-ill sepsis patients: a review article and literature to review
Sepsis, a life-threatening condition, commonly affecting critically ill patients, is a major cause of death worldwide. It is thus of great importance to determine the optimum management to cure this condition. This review article summarizes the role and effects of corticosteroids in the treatment of...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Greater Baltimore Medical Center
2021-11-01
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Series: | Journal of Community Hospital Internal Medicine Perspectives |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/20009666.2021.1964164 |
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author | Mohsin Mirza Maryam Zafar Mariam Siddiqui Anum Abbas Joseph Nahas Muazzam Mirza Abubakar Tauseef |
author_facet | Mohsin Mirza Maryam Zafar Mariam Siddiqui Anum Abbas Joseph Nahas Muazzam Mirza Abubakar Tauseef |
author_sort | Mohsin Mirza |
collection | DOAJ |
description | Sepsis, a life-threatening condition, commonly affecting critically ill patients, is a major cause of death worldwide. It is thus of great importance to determine the optimum management to cure this condition. This review article summarizes the role and effects of corticosteroids in the treatment of sepsis and septic shock, and to determine its mortality benefits. We used PubMed, Google scholar, Scopus, and Embase databases for literature review, and terminologies commonly searched were ‘sepsis’, ‘septic shock’, ‘therapeutic use’ and ‘corticosteroids’. In this review article, we reviewed a total of eight different articles being done in last 10 years, relevant to the clinical outcome and effects of corticosteroids. Among those, two demonstrated improved clinical outcomes, two showed both improved clinical outcomes and decreased mortality, three showed increased adverse effects, and the remaining one showed unequivocal results. |
first_indexed | 2024-04-11T03:54:25Z |
format | Article |
id | doaj.art-a8b3ec3e0eb84d48a4acf294d6e93c45 |
institution | Directory Open Access Journal |
issn | 2000-9666 |
language | English |
last_indexed | 2024-04-11T03:54:25Z |
publishDate | 2021-11-01 |
publisher | Greater Baltimore Medical Center |
record_format | Article |
series | Journal of Community Hospital Internal Medicine Perspectives |
spelling | doaj.art-a8b3ec3e0eb84d48a4acf294d6e93c452023-01-02T01:11:25ZengGreater Baltimore Medical CenterJournal of Community Hospital Internal Medicine Perspectives2000-96662021-11-0111682582910.1080/20009666.2021.19641641964164Role of steroids in critically-ill sepsis patients: a review article and literature to reviewMohsin Mirza0Maryam Zafar1Mariam Siddiqui2Anum Abbas3Joseph Nahas4Muazzam Mirza5Abubakar Tauseef6Creighton University School of MedicineDow University of Health Sciences, DUHSDow University of Health Sciences, DUHSUniversity of Nebraska Medical CenterCreighton University School of MedicineCreighton University School of MedicineCreighton University School of MedicineSepsis, a life-threatening condition, commonly affecting critically ill patients, is a major cause of death worldwide. It is thus of great importance to determine the optimum management to cure this condition. This review article summarizes the role and effects of corticosteroids in the treatment of sepsis and septic shock, and to determine its mortality benefits. We used PubMed, Google scholar, Scopus, and Embase databases for literature review, and terminologies commonly searched were ‘sepsis’, ‘septic shock’, ‘therapeutic use’ and ‘corticosteroids’. In this review article, we reviewed a total of eight different articles being done in last 10 years, relevant to the clinical outcome and effects of corticosteroids. Among those, two demonstrated improved clinical outcomes, two showed both improved clinical outcomes and decreased mortality, three showed increased adverse effects, and the remaining one showed unequivocal results.http://dx.doi.org/10.1080/20009666.2021.1964164rolesteroidsepsisreviewliteraurecritically ill |
spellingShingle | Mohsin Mirza Maryam Zafar Mariam Siddiqui Anum Abbas Joseph Nahas Muazzam Mirza Abubakar Tauseef Role of steroids in critically-ill sepsis patients: a review article and literature to review Journal of Community Hospital Internal Medicine Perspectives role steroid sepsis review literaure critically ill |
title | Role of steroids in critically-ill sepsis patients: a review article and literature to review |
title_full | Role of steroids in critically-ill sepsis patients: a review article and literature to review |
title_fullStr | Role of steroids in critically-ill sepsis patients: a review article and literature to review |
title_full_unstemmed | Role of steroids in critically-ill sepsis patients: a review article and literature to review |
title_short | Role of steroids in critically-ill sepsis patients: a review article and literature to review |
title_sort | role of steroids in critically ill sepsis patients a review article and literature to review |
topic | role steroid sepsis review literaure critically ill |
url | http://dx.doi.org/10.1080/20009666.2021.1964164 |
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