A Characterization of Dendritic Cells and Their Role in Immunotherapy in Glioblastoma: From Preclinical Studies to Clinical Trials

A Characterization of Dendritic Cells and Their Role in Immunotherapy in Glioblastoma: From Preclinical Studies to Clinical Trials

Glioblastoma (GBM) is the most common and fatal primary central nervous system malignancy in adults with a median survival of less than 15 months. Surgery, radiation, and chemotherapy are the standard of care and provide modest benefits in survival, but tumor recurrence is inevitable. The poor progn...

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Bibliographic Details
Main Authors: Siddhartha Srivastava, Christina Jackson, Timothy Kim, John Choi, Michael Lim
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cancers
Subjects:
dendritic cells
immunotherapy
checkpoint inhibition
glioblastoma
vaccine
plasmacytoid
myeloid
combination therapy
clinical trial
Online Access:https://www.mdpi.com/2072-6694/11/4/537

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