Non random distribution of genomic features in breakpoint regions involved in chronic myeloid leukemia cases with variant t(9;22) or additional chromosomal rearrangements

Non random distribution of genomic features in breakpoint regions involved in chronic myeloid leukemia cases with variant t(9;22) or additional chromosomal rearrangements

<p>Abstract</p> <p>Background</p> <p>The t(9;22)(q34;q11), generating the Philadelphia (Ph) chromosome, is found in more than 90% of patients with chronic myeloid leukemia (CML). As a result of the translocation, the 3' portion of the <it>ABL1 </it>onco...

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Bibliographic Details
Main Authors: Vicari Laura, Rossi Antonella, Casieri Paola, Coccaro Nicoletta, Zagaria Antonella, Anelli Luisa, Albano Francesco, Liso Vincenzo, Rocchi Mariano, Specchia Giorgina
Format: Article
Language:English
Published: BMC 2010-05-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/120

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