Not Everything Is as It Seems: A Case Series and Overview of Diseases Mimicking Antineutrophil Cytoplasmic Antibody-Associated Vasculitis
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a rare heterogeneous disease in which treatment must be initiated early to prevent irreversible organ damage and death. There are several diseases that can mimic AAV, even in the presence of positive ANCA serology and/or histo...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-09-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/19/6144 |
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| author | Eline Houben Pieter F. de Groot Yosta Vegting Josephine M. I. Vos Erfan Nur Marc L. Hilhorst A. E. (Liesbeth) Hak Arjan J. Kwakernaak |
| author_facet | Eline Houben Pieter F. de Groot Yosta Vegting Josephine M. I. Vos Erfan Nur Marc L. Hilhorst A. E. (Liesbeth) Hak Arjan J. Kwakernaak |
| author_sort | Eline Houben |
| collection | DOAJ |
| description | Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a rare heterogeneous disease in which treatment must be initiated early to prevent irreversible organ damage and death. There are several diseases that can mimic AAV, even in the presence of positive ANCA serology and/or histological evidence of vasculitis, as demonstrated in this case series. We reflect on the diagnostic approach of patients with AAV and provide an overview of AAV-mimicking diseases that can be considered in patients with atypical disease presentation or course. |
| first_indexed | 2024-03-10T21:42:59Z |
| format | Article |
| id | doaj.art-a8c0229530d54e42a021d62449fde3a8 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T21:42:59Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-a8c0229530d54e42a021d62449fde3a82023-11-19T14:34:42ZengMDPI AGJournal of Clinical Medicine2077-03832023-09-011219614410.3390/jcm12196144Not Everything Is as It Seems: A Case Series and Overview of Diseases Mimicking Antineutrophil Cytoplasmic Antibody-Associated VasculitisEline Houben0Pieter F. de Groot1Yosta Vegting2Josephine M. I. Vos3Erfan Nur4Marc L. Hilhorst5A. E. (Liesbeth) Hak6Arjan J. Kwakernaak7Department of Medicine, Division of Clinical Immunology and Allergy, Vasculitis Center of Expertise, Amsterdam University Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The NetherlandsDepartment of Medicine, Division of Clinical Immunology and Allergy, Vasculitis Center of Expertise, Amsterdam University Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The NetherlandsAmsterdam Institute for Infection and Immunity, Amsterdam University Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The NetherlandsDepartment of Hematology, Cancer Center Amsterdam, Amsterdam University Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The NetherlandsDepartment of Hematology, Cancer Center Amsterdam, Amsterdam University Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The NetherlandsAmsterdam Institute for Infection and Immunity, Amsterdam University Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The NetherlandsDepartment of Medicine, Division of Clinical Immunology and Allergy, Vasculitis Center of Expertise, Amsterdam University Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The NetherlandsDepartment of Medicine, Division of Clinical Immunology and Allergy, Vasculitis Center of Expertise, Amsterdam University Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The NetherlandsAntineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a rare heterogeneous disease in which treatment must be initiated early to prevent irreversible organ damage and death. There are several diseases that can mimic AAV, even in the presence of positive ANCA serology and/or histological evidence of vasculitis, as demonstrated in this case series. We reflect on the diagnostic approach of patients with AAV and provide an overview of AAV-mimicking diseases that can be considered in patients with atypical disease presentation or course.https://www.mdpi.com/2077-0383/12/19/6144ANCA-associated vasculitismimicking diseasemycobacterium avium complexcryoglobulinemic vasculitisNK/T-cell lymphoma |
| spellingShingle | Eline Houben Pieter F. de Groot Yosta Vegting Josephine M. I. Vos Erfan Nur Marc L. Hilhorst A. E. (Liesbeth) Hak Arjan J. Kwakernaak Not Everything Is as It Seems: A Case Series and Overview of Diseases Mimicking Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Journal of Clinical Medicine ANCA-associated vasculitis mimicking disease mycobacterium avium complex cryoglobulinemic vasculitis NK/T-cell lymphoma |
| title | Not Everything Is as It Seems: A Case Series and Overview of Diseases Mimicking Antineutrophil Cytoplasmic Antibody-Associated Vasculitis |
| title_full | Not Everything Is as It Seems: A Case Series and Overview of Diseases Mimicking Antineutrophil Cytoplasmic Antibody-Associated Vasculitis |
| title_fullStr | Not Everything Is as It Seems: A Case Series and Overview of Diseases Mimicking Antineutrophil Cytoplasmic Antibody-Associated Vasculitis |
| title_full_unstemmed | Not Everything Is as It Seems: A Case Series and Overview of Diseases Mimicking Antineutrophil Cytoplasmic Antibody-Associated Vasculitis |
| title_short | Not Everything Is as It Seems: A Case Series and Overview of Diseases Mimicking Antineutrophil Cytoplasmic Antibody-Associated Vasculitis |
| title_sort | not everything is as it seems a case series and overview of diseases mimicking antineutrophil cytoplasmic antibody associated vasculitis |
| topic | ANCA-associated vasculitis mimicking disease mycobacterium avium complex cryoglobulinemic vasculitis NK/T-cell lymphoma |
| url | https://www.mdpi.com/2077-0383/12/19/6144 |
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