Reproductive aging and elective fertility preservation

Abstract Reproductive aging is a natural process that occurs in all women, eventually leading to reproductive senescence and menopause. Over the past half century there has been a trend towards delayed motherhood. Postponing reproduction can increase the chance of a woman remaining involuntarily chi...

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Главные авторы: Rani Fritz, Sangita Jindal
Формат: Статья
Язык:English
Опубликовано: BMC 2018-08-01
Серии:Journal of Ovarian Research
Предметы:
Online-ссылка:http://link.springer.com/article/10.1186/s13048-018-0438-4
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author Rani Fritz
Sangita Jindal
author_facet Rani Fritz
Sangita Jindal
author_sort Rani Fritz
collection DOAJ
description Abstract Reproductive aging is a natural process that occurs in all women, eventually leading to reproductive senescence and menopause. Over the past half century there has been a trend towards delayed motherhood. Postponing reproduction can increase the chance of a woman remaining involuntarily childless as well as an increase in pregnancy complications in those that do achieve pregnancy at advanced maternal age. Despite the well-documented decrease in fecundity that occurs as a woman ages, reproductive aged women frequently overestimate the age at which a significant decline in fertility occurs and overestimate the success of assisted reproductive technologies (ART) to circumvent infertility. Oocyte cryopreservation enables women to achieve genetically related offspring in the event that they desire to postpone their childbearing to an age after which a significant decline in fertility occurs or in circumstances in which their reproductive potential is compromised due to medical pathology. Available success rates and safety data following oocyte cryopreservation have been reassuring and is not considered experimental according to the American Society for Reproductive Medicine and the European Society for Human Reproduction and Embryology. This review article will focus on an evidence-based discussion relating to reproductive aging and oocyte cryopreservation.
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spelling doaj.art-a8cbf9ed7723451b88b51a577f912be12023-01-02T08:54:22ZengBMCJournal of Ovarian Research1757-22152018-08-011111810.1186/s13048-018-0438-4Reproductive aging and elective fertility preservationRani Fritz0Sangita Jindal1Department of Obstetrics, Gynecology & Women’s Health, Albert Einstein College of Medicine/Montefiore Medical CenterDepartment of Obstetrics, Gynecology & Women’s Health, Albert Einstein College of Medicine/Montefiore Medical CenterAbstract Reproductive aging is a natural process that occurs in all women, eventually leading to reproductive senescence and menopause. Over the past half century there has been a trend towards delayed motherhood. Postponing reproduction can increase the chance of a woman remaining involuntarily childless as well as an increase in pregnancy complications in those that do achieve pregnancy at advanced maternal age. Despite the well-documented decrease in fecundity that occurs as a woman ages, reproductive aged women frequently overestimate the age at which a significant decline in fertility occurs and overestimate the success of assisted reproductive technologies (ART) to circumvent infertility. Oocyte cryopreservation enables women to achieve genetically related offspring in the event that they desire to postpone their childbearing to an age after which a significant decline in fertility occurs or in circumstances in which their reproductive potential is compromised due to medical pathology. Available success rates and safety data following oocyte cryopreservation have been reassuring and is not considered experimental according to the American Society for Reproductive Medicine and the European Society for Human Reproduction and Embryology. This review article will focus on an evidence-based discussion relating to reproductive aging and oocyte cryopreservation.http://link.springer.com/article/10.1186/s13048-018-0438-4Reproductive aging- oocyte cryopreservation- reproduction
spellingShingle Rani Fritz
Sangita Jindal
Reproductive aging and elective fertility preservation
Journal of Ovarian Research
Reproductive aging- oocyte cryopreservation- reproduction
title Reproductive aging and elective fertility preservation
title_full Reproductive aging and elective fertility preservation
title_fullStr Reproductive aging and elective fertility preservation
title_full_unstemmed Reproductive aging and elective fertility preservation
title_short Reproductive aging and elective fertility preservation
title_sort reproductive aging and elective fertility preservation
topic Reproductive aging- oocyte cryopreservation- reproduction
url http://link.springer.com/article/10.1186/s13048-018-0438-4
work_keys_str_mv AT ranifritz reproductiveagingandelectivefertilitypreservation
AT sangitajindal reproductiveagingandelectivefertilitypreservation