Intestinal epithelium-derived BMP controls stem cell self-renewal in Drosophila adult midgut

Intestinal epithelium-derived BMP controls stem cell self-renewal in Drosophila adult midgut

Stem cells are maintained in a specialized microenvironment called niche but the nature of stem cell niche remains poorly defined in many systems. Here we demonstrate that intestinal epithelium-derived BMP serves as a niche signal for intestinal stem cell (ISC) self-renewal in Drosophila adult midgu...

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Bibliographic Details
Main Authors: Aiguo Tian, Jin Jiang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-03-01
Series:eLife
Subjects:
stem cell niche
intestinal stem cell
midgut
self-renewal
BMP
regeneration
Online Access:https://elifesciences.org/articles/01857

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