Rational Engineering of a Flavoprotein Oxidase for Improved Direct Oxidation of Alcohols to Carboxylic Acids

Rational Engineering of a Flavoprotein Oxidase for Improved Direct Oxidation of Alcohols to Carboxylic Acids

The oxidation of alcohols to the corresponding carbonyl or carboxyl compounds represents a convenient strategy for the selective introduction of electrophilic carbon centres into carbohydrate-based starting materials. The O2-dependent oxidation of prim-alcohols by flavin-containing alcohol oxidases...

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Bibliographic Details
Main Authors: Mathias Pickl, Christoph K. Winkler, Silvia M. Glueck, Marco W. Fraaije, Kurt Faber
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Molecules
Subjects:
biocatalysis
alcohol oxidation
aldehyde oxidation
flavoprotein oxidase
protein design
Online Access:https://www.mdpi.com/1420-3049/22/12/2205

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