Moexipril and left ventricular hypertrophy
George S Chrysant1, PK NguyenUniversity of Oklahoma, 1Director, Advanced Cardiac Imaging, INTEGRIS Heart Hospital, Oklahoma City, OK, USAAbstract: Angiotensin-converting enzyme (ACE) inhibitors today are the standard therapy of patients with myocardial infarction and heart failure due to their prove...
Main Authors: | , |
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Format: | Article |
Language: | English |
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Dove Medical Press
2007-03-01
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Series: | Vascular Health and Risk Management |
Online Access: | https://www.dovepress.com/moexipril-and-left-ventricular-hypertrophy-peer-reviewed-article-VHRM |
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author | George S Chrysant PK Nguyen |
author_facet | George S Chrysant PK Nguyen |
author_sort | George S Chrysant |
collection | DOAJ |
description | George S Chrysant1, PK NguyenUniversity of Oklahoma, 1Director, Advanced Cardiac Imaging, INTEGRIS Heart Hospital, Oklahoma City, OK, USAAbstract: Angiotensin-converting enzyme (ACE) inhibitors today are the standard therapy of patients with myocardial infarction and heart failure due to their proven beneficial effects in left ventricular remodeling and left ventricular function. ACE inhibitors have also been demonstrated to lead to regression of left ventricular hypertrophy (LVH). It is believed that the mechanism of action of LVH regression with ACE inhibitors arises from more than simple blood pressure reduction. LVH is an important risk factor for cardiovascular disease morbidity and mortality independent of blood pressure. Moexipril hydrochloride is a long-acting, non-sulfhydryl ACE inhibitor that can be taken once daily for the treatment of hypertension. Moexipril has now also been demonstrated to have beneficial effects on LVH and can lead to LVH regression.Keywords: moexipril, ACE inhibitor, cardiovascular disease, left ventricular hypertropy |
first_indexed | 2024-12-10T21:41:13Z |
format | Article |
id | doaj.art-a8d09c08949f45b6b439e3dde42ab165 |
institution | Directory Open Access Journal |
issn | 1178-2048 |
language | English |
last_indexed | 2024-12-10T21:41:13Z |
publishDate | 2007-03-01 |
publisher | Dove Medical Press |
record_format | Article |
series | Vascular Health and Risk Management |
spelling | doaj.art-a8d09c08949f45b6b439e3dde42ab1652022-12-22T01:32:30ZengDove Medical PressVascular Health and Risk Management1178-20482007-03-01Volume 323301459Moexipril and left ventricular hypertrophyGeorge S ChrysantPK NguyenGeorge S Chrysant1, PK NguyenUniversity of Oklahoma, 1Director, Advanced Cardiac Imaging, INTEGRIS Heart Hospital, Oklahoma City, OK, USAAbstract: Angiotensin-converting enzyme (ACE) inhibitors today are the standard therapy of patients with myocardial infarction and heart failure due to their proven beneficial effects in left ventricular remodeling and left ventricular function. ACE inhibitors have also been demonstrated to lead to regression of left ventricular hypertrophy (LVH). It is believed that the mechanism of action of LVH regression with ACE inhibitors arises from more than simple blood pressure reduction. LVH is an important risk factor for cardiovascular disease morbidity and mortality independent of blood pressure. Moexipril hydrochloride is a long-acting, non-sulfhydryl ACE inhibitor that can be taken once daily for the treatment of hypertension. Moexipril has now also been demonstrated to have beneficial effects on LVH and can lead to LVH regression.Keywords: moexipril, ACE inhibitor, cardiovascular disease, left ventricular hypertropyhttps://www.dovepress.com/moexipril-and-left-ventricular-hypertrophy-peer-reviewed-article-VHRM |
spellingShingle | George S Chrysant PK Nguyen Moexipril and left ventricular hypertrophy Vascular Health and Risk Management |
title | Moexipril and left ventricular hypertrophy |
title_full | Moexipril and left ventricular hypertrophy |
title_fullStr | Moexipril and left ventricular hypertrophy |
title_full_unstemmed | Moexipril and left ventricular hypertrophy |
title_short | Moexipril and left ventricular hypertrophy |
title_sort | moexipril and left ventricular hypertrophy |
url | https://www.dovepress.com/moexipril-and-left-ventricular-hypertrophy-peer-reviewed-article-VHRM |
work_keys_str_mv | AT georgeschrysant moexiprilandleftventricularhypertrophy AT pknguyen moexiprilandleftventricularhypertrophy |