Moexipril and left ventricular hypertrophy

George S Chrysant1, PK NguyenUniversity of Oklahoma, 1Director, Advanced Cardiac Imaging, INTEGRIS Heart Hospital, Oklahoma City, OK, USAAbstract: Angiotensin-converting enzyme (ACE) inhibitors today are the standard therapy of patients with myocardial infarction and heart failure due to their prove...

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Main Authors: George S Chrysant, PK Nguyen
Format: Article
Language:English
Published: Dove Medical Press 2007-03-01
Series:Vascular Health and Risk Management
Online Access:https://www.dovepress.com/moexipril-and-left-ventricular-hypertrophy-peer-reviewed-article-VHRM
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author George S Chrysant
PK Nguyen
author_facet George S Chrysant
PK Nguyen
author_sort George S Chrysant
collection DOAJ
description George S Chrysant1, PK NguyenUniversity of Oklahoma, 1Director, Advanced Cardiac Imaging, INTEGRIS Heart Hospital, Oklahoma City, OK, USAAbstract: Angiotensin-converting enzyme (ACE) inhibitors today are the standard therapy of patients with myocardial infarction and heart failure due to their proven beneficial effects in left ventricular remodeling and left ventricular function. ACE inhibitors have also been demonstrated to lead to regression of left ventricular hypertrophy (LVH). It is believed that the mechanism of action of LVH regression with ACE inhibitors arises from more than simple blood pressure reduction. LVH is an important risk factor for cardiovascular disease morbidity and mortality independent of blood pressure. Moexipril hydrochloride is a long-acting, non-sulfhydryl ACE inhibitor that can be taken once daily for the treatment of hypertension. Moexipril has now also been demonstrated to have beneficial effects on LVH and can lead to LVH regression.Keywords: moexipril, ACE inhibitor, cardiovascular disease, left ventricular hypertropy
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spelling doaj.art-a8d09c08949f45b6b439e3dde42ab1652022-12-22T01:32:30ZengDove Medical PressVascular Health and Risk Management1178-20482007-03-01Volume 323301459Moexipril and left ventricular hypertrophyGeorge S ChrysantPK NguyenGeorge S Chrysant1, PK NguyenUniversity of Oklahoma, 1Director, Advanced Cardiac Imaging, INTEGRIS Heart Hospital, Oklahoma City, OK, USAAbstract: Angiotensin-converting enzyme (ACE) inhibitors today are the standard therapy of patients with myocardial infarction and heart failure due to their proven beneficial effects in left ventricular remodeling and left ventricular function. ACE inhibitors have also been demonstrated to lead to regression of left ventricular hypertrophy (LVH). It is believed that the mechanism of action of LVH regression with ACE inhibitors arises from more than simple blood pressure reduction. LVH is an important risk factor for cardiovascular disease morbidity and mortality independent of blood pressure. Moexipril hydrochloride is a long-acting, non-sulfhydryl ACE inhibitor that can be taken once daily for the treatment of hypertension. Moexipril has now also been demonstrated to have beneficial effects on LVH and can lead to LVH regression.Keywords: moexipril, ACE inhibitor, cardiovascular disease, left ventricular hypertropyhttps://www.dovepress.com/moexipril-and-left-ventricular-hypertrophy-peer-reviewed-article-VHRM
spellingShingle George S Chrysant
PK Nguyen
Moexipril and left ventricular hypertrophy
Vascular Health and Risk Management
title Moexipril and left ventricular hypertrophy
title_full Moexipril and left ventricular hypertrophy
title_fullStr Moexipril and left ventricular hypertrophy
title_full_unstemmed Moexipril and left ventricular hypertrophy
title_short Moexipril and left ventricular hypertrophy
title_sort moexipril and left ventricular hypertrophy
url https://www.dovepress.com/moexipril-and-left-ventricular-hypertrophy-peer-reviewed-article-VHRM
work_keys_str_mv AT georgeschrysant moexiprilandleftventricularhypertrophy
AT pknguyen moexiprilandleftventricularhypertrophy