Incidence of cleft Lip and palate in the state of Andhra Pradesh, South India
Objective: To assess the incidence of cleft lip and palate defects in the state of Andhra Pradesh, India. Design Setting: The study was conducted in 2001 in the state of Andhra Pradesh, India. The state has a population of 76 million. Three districts, Cuddapah, Medak and Krishna, were identified for...
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| Format: | Article |
| Language: | English |
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Thieme Medical Publishers, Inc.
2010-07-01
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| Series: | Indian Journal of Plastic Surgery |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1699433 |
| _version_ | 1817989535526551552 |
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| author | Srinivas Gosla Reddy Rajgopal R. Reddy Ewald M. Bronkhorst Rajendra Prasad Anke M. Ettema Hermann F. Sailer Stefaan J. Bergé |
| author_facet | Srinivas Gosla Reddy Rajgopal R. Reddy Ewald M. Bronkhorst Rajendra Prasad Anke M. Ettema Hermann F. Sailer Stefaan J. Bergé |
| author_sort | Srinivas Gosla Reddy |
| collection | DOAJ |
| description | Objective: To assess the incidence of cleft lip and palate defects in the state of Andhra Pradesh, India. Design Setting: The study was conducted in 2001 in the state of Andhra Pradesh, India. The state has a population of 76 million. Three districts, Cuddapah, Medak and Krishna, were identified for this study owing to their diversity. They were urban, semi-urban and rural, respectively. Literacy rates and consanguinity of the parents was elicited and was compared to national averages to find correlations to cleft births. Type and side of cleft were recorded to compare with other studies around the world and other parts of India. Results: The birth rate of clefts was found to be 1.09 for every 1000 live births. This study found that 65% of the children born with clefts were males. The distribution of the type of cleft showed 33% had CL, 64% had CLP, 2% had CP and 1% had rare craniofacial clefts. Unilateral cleft lips were found in 79% of the patients. Of the unilateral cleft lips 64% were left sided. There was a significant correlation of children with clefts being born to parents who shared a consanguineous relationship and those who were illiterate with the odds ratio between 5.25 and 7.21 for consanguinity and between 1.55 and 5.85 for illiteracy, respectively. Conclusion: The birth rate of clefts was found to be comparable with other Asian studies, but lower than found in other studies in Caucasian populations and higher than in African populations. The incidence was found to be similar to other studies done in other parts of India. The distribution over the various types of cleft was comparable to that found in other studies. |
| first_indexed | 2024-04-14T00:48:08Z |
| format | Article |
| id | doaj.art-a8d4856ff2a44effa397b476dffae1f6 |
| institution | Directory Open Access Journal |
| issn | 0970-0358 1998-376X |
| language | English |
| last_indexed | 2024-04-14T00:48:08Z |
| publishDate | 2010-07-01 |
| publisher | Thieme Medical Publishers, Inc. |
| record_format | Article |
| series | Indian Journal of Plastic Surgery |
| spelling | doaj.art-a8d4856ff2a44effa397b476dffae1f62022-12-22T02:21:56ZengThieme Medical Publishers, Inc.Indian Journal of Plastic Surgery0970-03581998-376X2010-07-01430218418910.1055/s-0039-1699433Incidence of cleft Lip and palate in the state of Andhra Pradesh, South IndiaSrinivas Gosla Reddy0Rajgopal R. Reddy1Ewald M. Bronkhorst2Rajendra Prasad3Anke M. Ettema4Hermann F. Sailer5Stefaan J. Bergé6GSR Institute of Craniofacial Surgery, Hyderabad, Andhra Pradesh, IndiaGSR Institute of Craniofacial Surgery, Hyderabad, Andhra Pradesh, IndiaRadboud University Nijmegen Medical Center, Nijmegen, The NetherlandsDepartment of Cariology and Preventive Dentistry, Nijmegen, The NetherlandsA. B. Shetty Memorial Dental College and Hospital, Mangalore, Karnataka, IndiaDepartment of Oral and Maxillofacial Surgery, Radboud University Nijmegen Medical Center, Nijmegen, The NetherlandsA. B. Shetty Memorial Dental College and Hospital, Mangalore, Karnataka, IndiaObjective: To assess the incidence of cleft lip and palate defects in the state of Andhra Pradesh, India. Design Setting: The study was conducted in 2001 in the state of Andhra Pradesh, India. The state has a population of 76 million. Three districts, Cuddapah, Medak and Krishna, were identified for this study owing to their diversity. They were urban, semi-urban and rural, respectively. Literacy rates and consanguinity of the parents was elicited and was compared to national averages to find correlations to cleft births. Type and side of cleft were recorded to compare with other studies around the world and other parts of India. Results: The birth rate of clefts was found to be 1.09 for every 1000 live births. This study found that 65% of the children born with clefts were males. The distribution of the type of cleft showed 33% had CL, 64% had CLP, 2% had CP and 1% had rare craniofacial clefts. Unilateral cleft lips were found in 79% of the patients. Of the unilateral cleft lips 64% were left sided. There was a significant correlation of children with clefts being born to parents who shared a consanguineous relationship and those who were illiterate with the odds ratio between 5.25 and 7.21 for consanguinity and between 1.55 and 5.85 for illiteracy, respectively. Conclusion: The birth rate of clefts was found to be comparable with other Asian studies, but lower than found in other studies in Caucasian populations and higher than in African populations. The incidence was found to be similar to other studies done in other parts of India. The distribution over the various types of cleft was comparable to that found in other studies.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1699433cleft lip & paplate incidencecleft lipcleft palate |
| spellingShingle | Srinivas Gosla Reddy Rajgopal R. Reddy Ewald M. Bronkhorst Rajendra Prasad Anke M. Ettema Hermann F. Sailer Stefaan J. Bergé Incidence of cleft Lip and palate in the state of Andhra Pradesh, South India Indian Journal of Plastic Surgery cleft lip & paplate incidence cleft lip cleft palate |
| title | Incidence of cleft Lip and palate in the state of Andhra Pradesh, South India |
| title_full | Incidence of cleft Lip and palate in the state of Andhra Pradesh, South India |
| title_fullStr | Incidence of cleft Lip and palate in the state of Andhra Pradesh, South India |
| title_full_unstemmed | Incidence of cleft Lip and palate in the state of Andhra Pradesh, South India |
| title_short | Incidence of cleft Lip and palate in the state of Andhra Pradesh, South India |
| title_sort | incidence of cleft lip and palate in the state of andhra pradesh south india |
| topic | cleft lip & paplate incidence cleft lip cleft palate |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1699433 |
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