Long noncoding RNA MAPKAPK5-AS1 promoted lipopolysaccharide-induced inflammatory damage in the myocardium by sponging microRNA-124-3p/E2F3

Long noncoding RNA MAPKAPK5-AS1 promoted lipopolysaccharide-induced inflammatory damage in the myocardium by sponging microRNA-124-3p/E2F3

Abstract Background Myocardial dysfunction caused by sepsis (SIMD) leads to high mortality in critically ill patients. We investigated the function and mechanism of long non-coding RNA MAPKAPK5-AS1 (lncRNA MAPKAPK-AS1) on lipopolysaccharide (LPS)-induced inflammation response in vivo and in vitro. M...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Weiwei Chen, Guangyuan Gao, Mengjie Yan, Ming Yu, Kaiyao Shi, Ping Yang
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: BMC 2021-10-01
Sraith:Molecular Medicine
Ábhair:
MAPKAPK5-AS1
Lipopolysaccharide
Inflammatory response
microRNA-124-3p
E2F3
Rochtain ar líne:https://doi.org/10.1186/s10020-021-00385-1

Ar líne

https://doi.org/10.1186/s10020-021-00385-1

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