Influenza A virus hemagglutinin glycosylation compensates for antibody escape fitness costs.

Influenza A virus hemagglutinin glycosylation compensates for antibody escape fitness costs.

Rapid antigenic evolution enables the persistence of seasonal influenza A and B viruses in human populations despite widespread herd immunity. Understanding viral mechanisms that enable antigenic evolution is critical for designing durable vaccines and therapeutics. Here, we utilize the primerID met...

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Podrobná bibliografie
Hlavní autoři: Ivan Kosik, William L Ince, Lauren E Gentles, Andrew J Oler, Martina Kosikova, Matthew Angel, Javier G Magadán, Hang Xie, Christopher B Brooke, Jonathan W Yewdell
Médium: Článek
Jazyk:English
Vydáno: Public Library of Science (PLoS) 2018-01-01
Edice:PLoS Pathogens
On-line přístup:http://europepmc.org/articles/PMC5773227?pdf=render

Internet

http://europepmc.org/articles/PMC5773227?pdf=render

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