Genome-Wide DNA Methylation and LncRNA-Associated DNA Methylation in Metformin-Treated and -Untreated Diabetes

Genome-Wide DNA Methylation and LncRNA-Associated DNA Methylation in Metformin-Treated and -Untreated Diabetes

Metformin, which is used as a first line treatment for type 2 diabetes mellitus (T2DM), has been shown to affect epigenetic patterns. In this study, we investigated the DNA methylation and potential lncRNA modifications in metformin-treated and newly diagnosed adults with T2DM. Genome-wide DNA methy...

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Bibliographic Details
Main Authors: Wendy L. Solomon, Stanton B. E. Hector, Shanel Raghubeer, Rajiv T. Erasmus, Andre P. Kengne, Tandi E. Matsha
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Epigenomes
Subjects:
metformin
DNA methylation
lncRNA
diabetes mellitus
Africa
Online Access:https://www.mdpi.com/2075-4655/4/3/19

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