Oxysterol 7-α Hydroxylase (CYP7B1) Attenuates Metabolic-Associated Fatty Liver Disease in Mice at Thermoneutrality
Ambient temperature is an important determinant of both the alternative bile acid synthesis pathway controlled by oxysterol 7-α hydroxylase (CYP7B1) and the progression of metabolic-associated fatty liver disease (MAFLD). Here, we investigated whether CYP7B1 is involved in the etiology of MAFLD unde...
Auteurs principaux: | Ioannis Evangelakos, Dorothee Schwinge, Anna Worthmann, Clara John, Niklas Roeder, Paul Pertzborn, Janina Behrens, Christoph Schramm, Ludger Scheja, Joerg Heeren |
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Format: | Article |
Langue: | English |
Publié: |
MDPI AG
2021-10-01
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Collection: | Cells |
Sujets: | |
Accès en ligne: | https://www.mdpi.com/2073-4409/10/10/2656 |
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