Preparation and in vivo evaluation of an intravenous emulsion loaded with an aprepitant-phospholipid complex

Preparation and in vivo evaluation of an intravenous emulsion loaded with an aprepitant-phospholipid complex

AbstractIn present, there was no detailed report on the formulation optimization and quality evaluation of aprepitant (APT) injectable lipid emulsion (APT-IE). The aim of the present investigation was to prepare and evaluate its properties of APT-IE loaded with an APT phospholipid complex (APT-PC) i...

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Bibliographic Details
Main Authors: Yan Li, Hong Yin, Chensi Wu, Jia He, Chunyan Wang, Bo Ren, Heping Wang, Dandan Geng, Yirong Zhang, Ligang Zhao
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Drug Delivery
Subjects:
Aprepitant
lipid injectable emulsion
response surface methodology
pharmacokinetics
tissue distribution
Online Access:https://www.tandfonline.com/doi/10.1080/10717544.2023.2183834

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