Bone Mineral Content Prediction by Bioelectrical Impedance Analysis in Children and Adolescents Diagnosed with HIV Infection: Comparison with Dual Energy X-ray Absorptiometry: A Cross-Sectional Study
A body composition analysis has been used to investigate alterations on body tissues in children and adolescents diagnosed with human immunodeficiency virus (HIV) infection, such as low bone mineral content (BMC). The study aimed to developed equations to estimate the BMC in children and adolescents...
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MDPI AG
2022-12-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/12/23/12466 |
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| author | João Antônio Chula de Castro Luiz Rodrigo Augustemak de Lima Diego Augusto Santos Silva |
| author_facet | João Antônio Chula de Castro Luiz Rodrigo Augustemak de Lima Diego Augusto Santos Silva |
| author_sort | João Antônio Chula de Castro |
| collection | DOAJ |
| description | A body composition analysis has been used to investigate alterations on body tissues in children and adolescents diagnosed with human immunodeficiency virus (HIV) infection, such as low bone mineral content (BMC). The study aimed to developed equations to estimate the BMC in children and adolescents diagnosed with HIV based on a bioelectrical impedance analysis (BIA) using dual energy X-ray absorptiometry (DXA) as a reference method. This is a cross-sectional study conducted with children and adolescents diagnosed with HIV infection. Their body composition was evaluated by BIA and DXA. Linear multiple regression models were constructed to estimate the BMC. Sixty-four children and adolescents aged 8–15 years (12.22 ± 2.13) who were diagnosed with HIV infection participated in the study. The models were substantially correlated with the BMC values, and they explained 82–91% of the BMC, with no differences between DXA and values as estimated by the models. The model with the highest estimate of the BMC (91% of explanation) and the lowest error (SEE of 0.011 kg) included the following variables: body mass, fat mass, total 50 kHz reactance, TCD4 lymphocytes, antiretroviral therapy type, and %TCD4 lymphocytes. The models had a clinically acceptable correlation and low SEE values. The BIA was suitable to estimate the BMC in children and adolescents diagnosed with HIV. |
| first_indexed | 2024-03-09T17:52:33Z |
| format | Article |
| id | doaj.art-a8ded8e3e98f4fbea7c3971f6391220a |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-09T17:52:33Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-a8ded8e3e98f4fbea7c3971f6391220a2023-11-24T10:36:58ZengMDPI AGApplied Sciences2076-34172022-12-0112231246610.3390/app122312466Bone Mineral Content Prediction by Bioelectrical Impedance Analysis in Children and Adolescents Diagnosed with HIV Infection: Comparison with Dual Energy X-ray Absorptiometry: A Cross-Sectional StudyJoão Antônio Chula de Castro0Luiz Rodrigo Augustemak de Lima1Diego Augusto Santos Silva2Research Group in Kinanthropometry and Human Performance, Sports Center, Federal University of Santa Catarina, Florianópolis 88040-900, SC, BrazilResearch Group on Biodynamics of Human Performance and Health, Institute of Physical Education and Sport, Federal University of Alagoas, Maceió 57072-900, AL, BrazilResearch Group in Kinanthropometry and Human Performance, Sports Center, Federal University of Santa Catarina, Florianópolis 88040-900, SC, BrazilA body composition analysis has been used to investigate alterations on body tissues in children and adolescents diagnosed with human immunodeficiency virus (HIV) infection, such as low bone mineral content (BMC). The study aimed to developed equations to estimate the BMC in children and adolescents diagnosed with HIV based on a bioelectrical impedance analysis (BIA) using dual energy X-ray absorptiometry (DXA) as a reference method. This is a cross-sectional study conducted with children and adolescents diagnosed with HIV infection. Their body composition was evaluated by BIA and DXA. Linear multiple regression models were constructed to estimate the BMC. Sixty-four children and adolescents aged 8–15 years (12.22 ± 2.13) who were diagnosed with HIV infection participated in the study. The models were substantially correlated with the BMC values, and they explained 82–91% of the BMC, with no differences between DXA and values as estimated by the models. The model with the highest estimate of the BMC (91% of explanation) and the lowest error (SEE of 0.011 kg) included the following variables: body mass, fat mass, total 50 kHz reactance, TCD4 lymphocytes, antiretroviral therapy type, and %TCD4 lymphocytes. The models had a clinically acceptable correlation and low SEE values. The BIA was suitable to estimate the BMC in children and adolescents diagnosed with HIV.https://www.mdpi.com/2076-3417/12/23/12466acquired immunodeficiency syndromebody compositionlinear modelsbone massvaliditymeasurement error |
| spellingShingle | João Antônio Chula de Castro Luiz Rodrigo Augustemak de Lima Diego Augusto Santos Silva Bone Mineral Content Prediction by Bioelectrical Impedance Analysis in Children and Adolescents Diagnosed with HIV Infection: Comparison with Dual Energy X-ray Absorptiometry: A Cross-Sectional Study Applied Sciences acquired immunodeficiency syndrome body composition linear models bone mass validity measurement error |
| title | Bone Mineral Content Prediction by Bioelectrical Impedance Analysis in Children and Adolescents Diagnosed with HIV Infection: Comparison with Dual Energy X-ray Absorptiometry: A Cross-Sectional Study |
| title_full | Bone Mineral Content Prediction by Bioelectrical Impedance Analysis in Children and Adolescents Diagnosed with HIV Infection: Comparison with Dual Energy X-ray Absorptiometry: A Cross-Sectional Study |
| title_fullStr | Bone Mineral Content Prediction by Bioelectrical Impedance Analysis in Children and Adolescents Diagnosed with HIV Infection: Comparison with Dual Energy X-ray Absorptiometry: A Cross-Sectional Study |
| title_full_unstemmed | Bone Mineral Content Prediction by Bioelectrical Impedance Analysis in Children and Adolescents Diagnosed with HIV Infection: Comparison with Dual Energy X-ray Absorptiometry: A Cross-Sectional Study |
| title_short | Bone Mineral Content Prediction by Bioelectrical Impedance Analysis in Children and Adolescents Diagnosed with HIV Infection: Comparison with Dual Energy X-ray Absorptiometry: A Cross-Sectional Study |
| title_sort | bone mineral content prediction by bioelectrical impedance analysis in children and adolescents diagnosed with hiv infection comparison with dual energy x ray absorptiometry a cross sectional study |
| topic | acquired immunodeficiency syndrome body composition linear models bone mass validity measurement error |
| url | https://www.mdpi.com/2076-3417/12/23/12466 |
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