Concomitant use of magnesium oxide significantly decreases absorption of levodopa preparations in patients with Parkinson’s disease

Introduction: Constipation is one of the most frequent non-motor symptoms of Parkinson's disease (PD), and magnesium oxide (MgO) is a frequently used laxative. This study aimed to investigate the effect of concomitant use of MgO on the pharmacokinetics of levodopa preparations in patients with...

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Bibliographic Details
Main Authors: Noriyuki Miyaue, Hayato Yabe, Masahiro Nagai
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Clinical Parkinsonism & Related Disorders
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590112523000452