Complementary gene regulation by NRF1 and NRF2 protects against hepatic cholesterol overload

Summary: Hepatic cholesterol overload promotes steatohepatitis. Insufficient understanding of liver stress defense impedes therapy development. Here, we elucidate the role of stress defense transcription factors, nuclear factor erythroid 2 related factor-1 (NRF1) and -2 (NRF2), in counteracting chol...

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Bibliographic Details
Main Authors:	May G. Akl, Lei Li, Raquel Baccetto, Sadhna Phanse, Qingzhou Zhang, Michael J. Trites, Sherin McDonald, Hiroyuki Aoki, Mohan Babu, Scott B. Widenmaier
Format:	Article
Language:	English
Published:	Elsevier 2023-04-01
Series:	Cell Reports
Subjects:	CP: Metabolism
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124723004102

Complementary gene regulation by NRF1 and NRF2 protects against hepatic cholesterol overload by May G. Akl, Lei Li, Raquel Baccetto, Sadhna Phanse, Qingzhou Zhang, Michael J. Trites, Sherin McDonald, Hiroyuki Aoki, Mohan Babu, Scott B. Widenmaier

Published 2023-07-01

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Complementary gene regulation by NRF1 and NRF2 protects against hepatic cholesterol overload

Complementary gene regulation by NRF1 and NRF2 protects against hepatic cholesterol overload by May G. Akl, Lei Li, Raquel Baccetto, Sadhna Phanse, Qingzhou Zhang, Michael J. Trites, Sherin McDonald, Hiroyuki Aoki, Mohan Babu, Scott B. Widenmaier

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