A genetic approach to the recruitment of PRC2 at the HoxD locus.
Polycomb group (PcG) proteins are essential for the repression of key factors during early development. In Drosophila, the polycomb repressive complexes (PRC) associate with defined polycomb response DNA elements (PREs). In mammals, however, the mechanisms underlying polycomb recruitment at targeted...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-11-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC3820793?pdf=render |